Fig. 5

MSCs promote RAW264.7 apoptosis, and low concentration of MSC-CM facilitates LX-2 apoptosis and inhibition of proliferation. a Co-culture of RAW264.7 and MSCs induced massive apoptosis of RAW264.7 48 h later, shown using a fluorescent live/dead assay. b A low concentration of MSC-CM suppressed LX-2 proliferation 48 h later. c A low concentration of MSC-CM increased LX-2 apoptosis 48 h later, shown using a fluorescent live/dead assay. d Percentage of apoptosis for co-culture and RAW264.7-alone conditions. e Percentage of apoptosis for co-culture and LX-2-alone conditions. f Division index analysis of co-culture and LX-2-alone conditions. Experiments were performed in triplicate. Data are shown as mean ± standard deviation. *P < 0.05; **P < 0.01; ***P < 0.001