Table 4 Proteins preferential to either HFpEF or control groups

Proteins preferentially found in HFpEF group

SAA2

P0DJI9

Serum amyloid A-2 protein

0.0019

SAA1

P0DJI8

Serum amyloid A-1 protein

0.0019

PHF3

Q92576

PHD finger protein 3

0.0090

RGPD5

Q99666

RANBP2-like and GRIP domain-containing protein 5/6

0.0123

RGPD8

O14715

RANBP2-like and GRIP domain-containing protein 8

0.0124

YMEL1

Q96TA2

ATP-dependent zinc metalloprotease YME1L1

0.0256

FHR2

P36980

Complement factor H-related protein 2

0.0269

RGPD3

A6NKT7

RanBP2-like and GRIP domain-containing protein 3

0.0278

CG010

Q9HAC7

CaiB/baiF CoA-transferase family protein C7orf10

0.0279

RRBP1

Q9P2E9

Ribosome-binding protein 1

0.0279

ZNF79

Q15937

Zinc finger protein 79

0.0279

DCNL5

Q9BTE7

DCN1-like protein 5

0.0279

RECQ1

P46063

ATP-dependent DNA helicase Q1

0.0283

PERQ2

Q6Y7W6

PERQ amino acid-rich with GYF domain-containing protein 2

0.0285

MBD5

Q9P267

Methyl-CpG-binding domain protein 5

0.0286

GPCP1

Q9NPB8

Glycerophosphocholine phosphodiesterase GPCPD1

0.0286

NOL10

Q9BSC4

Nucleolar protein 10

0.0351

LBP

P18428

Lipopolysaccharide-binding protein

0.0432

AFF1

P51825

AF4/FMR2 family member 1

0.0442

SOX30

O94993

Transcription factor SOX-30

0.0458

DCP1A

Q9NPI6

mRNA-decapping enzyme 1A

0.0465

AN20B

Q5CZ79

Ankyrin repeat domain-containing protein 20B

0.0468

TCOF

Q13428

Treacle protein

0.0479

MEN1

O00255

Menin

0.0486

S10A8

P05109

S100A8

0.0808

Proteins preferentially found in control group

MY15B

Q96JP2

Putative unconventional myosin-XVB

0.0012

ASXL3

Q9C0F0

Putative Polycomb group protein ASXL3

0.0045

CC020

Q9NX02

NACHT, LRR and PYD domains-containing protein 2

0.0045

TEKT1

Q969V4

Tektin-1

0.0070

SEP10

Q9P0V9

Septin-10 OS = Homo sapiens

0.0103

LMNB2

Q03252

Lamin-B2 OS = Homo sapiens

0.0103

ZN469

Q96JG9

Zinc finger protein 469

0.0146

PARI

Q9NWS1

PCNA-interacting partner

0.0148

NOP2

P46087

Putative ribosomal RNA methyltransferase NOP2

0.0148

FIGL2

A6NMB9

Putative fidgetin-like protein 2

0.0148

MCTS1

Q9ULC4

Malignant T-cell-amplified sequence 1

0.0148

TANC2

Q9HCD6

Protein TANC2

0.0148

HEM0

P22557

5-aminolevulinate synthase, erythroid-specific, mitochondrial

0.0148

PRP6

O94906

Pre-mRNA-processing factor 6

0.0148

TACC2

O95359

Transforming acidic coiled-coil-containing protein 2

0.0200

SMC3

Q9UQE7

Structural maintenance of chromosomes protein 3

0.0261

GTF2I

P78347

General transcription factor II-I

0.0262

CI084

Q5VXU9

Uncharacterized protein

0.0268

CCS

O14618

Copper chaperone for superoxide dismutase

0.0294

COX6C

P09669

Cytochrome c oxidase subunit 6C

0.0324

INT11

Q5TA45

Integrator complex subunit 11

0.0352

DCLK1

O15075

Serine/threonine-protein kinase DCLK1

0.0363

SSH1

Q8WYL5

Protein phosphatase Slingshot homolog 1

0.0380

PJA1

Q8NG27

E3 ubiquitin-protein ligase Praja-1

0.0390

BRK1

Q8WUW1

Protein BRICK1

0.0422

UBP44

Q9H0E7

Ubiquitin carboxyl-terminal hydrolase 44

0.0422

PLCG2

P16885

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

0.0428

IGS22

Q8N9C0

Immunoglobulin superfamily member 22

0.0431

RPGFL

Q9UHV5

Rap guanine nucleotide exchange factor-like 1

0.0431

CN070

Q86TU6

Putative uncharacterized protein encoded by LINC00523

0.0431

TRI35

Q9UPQ4

Tripartite motif-containing protein 35

0.0431

TOPB1

Q92547

DNA topoisomerase 2-binding protein 1

0.0431

R3HD4

Q96D70

R3H domain-containing protein 4

0.0431

ABR

Q12979

Active breakpoint cluster region-related protein

0.0431

ZN441

Q8N8Z8

Zinc finger protein 441

0.0431

ZN451

Q9Y4E5

Zinc finger protein 451

0.0431

DCE2

Q05329

Glutamate decarboxylase 2

0.0431

RAB31

Q13636

Ras-related protein Rab-31

0.0431

PDE3A

Q14432

cGMP-inhibited 3′, 5′-cyclic phosphodiesterase A

0.0431

TRPM2

O94759

Transient receptor potential channel subfamily M member 2

0.0431

C163B

Q9NR16

Scavenger receptor cysteine-rich type 1 protein M160

0.0431

CA094

Q6P1W5

Uncharacterized protein C1orf94

0.0431

RSBN1

Q5VWQ0

Round spermatid basic protein 1

0.0431

GRM8

O00222

Metabotropic glutamate receptor 8

0.0431

KLHL7

Q8IXQ5

Kelch-like protein 7

0.0431

SHAN3

Q9BYB0

SH3 and multiple ankyrin repeat domains protein 3

0.0431

TTI1

O43156

TELO2-interacting protein 1 homolog

0.0431

FMO4

P31512

Dimethylaniline monooxygenase [N-oxide-forming] 4

0.0431

RARB

P10826

Retinoic acid receptor beta

0.0431

UTY

O14607

Histone demethylase UTY

0.0431

SLK

Q9H2G2

STE20-like serine/threonine-protein kinase

0.0431

RB39B

Q96DA2

Ras-related protein Rab-39B

0.0435

RB43L

A6NDJ8

Putative Rab-43-like protein

0.0435

RAB4B

P61018

Ras-related protein Rab-4B

0.0435

RAB12

Q6IQ22

Ras-related protein Rab-12

0.0435

RAB43

Q86YS6

Ras-related protein Rab-43

0.0435

RAB30

Q15771

Ras-related protein Rab-30

0.0435

GRM7

Q14831

Metabotropic glutamate receptor 7

0.0435

ZNF67

Q15940

Putative zinc finger protein 726P1

0.0435

FAKD5

Q7L8L6

FAST kinase domain-containing protein 5

0.0435

ZNF98

A6NK75

Zinc finger protein 98

0.0435

MFSD9

Q8NBP5

Major facilitator superfamily domain-containing protein 9

0.0435

RECK

O95980

Reversion-inducing cysteine-rich protein with Kazal motifs

0.0435

AL1A3

P47895

Aldehyde dehydrogenase family 1 member A3

0.0435

VP37C

A5D8V6

Vacuolar protein sorting-associated protein 37C

0.0435

ZN492

Q9P255

Zinc finger protein 492

0.0435

VPS29

Q9UBQ0

Vacuolar protein sorting-associated protein 29

0.0435

HNRCL

O60812

Heterogeneous nuclear ribonucleoprotein C-like 1

0.0435

DHRS7

Q9Y394

Dehydrogenase/reductase SDR family member 7

0.0452

BRD8

Q9H0E9

Bromodomain-containing protein 8

0.0455

IF2P

O60841

Eukaryotic translation initiation factor 5B

0.0455

GDPD3

Q7L5L3

Glycerophosphodiesterase domain-containing protein 3

0.0456

SYSC

P49591

Serine–tRNA ligase, cytoplasmic

0.0465

NEK9

Q8TD19

Serine/threonine-protein kinase Nek9

0.0473