Table 3 Recoveries of lymphocyte subpopulations after ATG-conditioned haploHSCT, cells/μL
|  | Group | CD19+ | CD3+ | CD4+ | CD8+ | CD4+CD45RA+ | CD4+CD45RO+ | CD4+CD28+ | CD8+CD28+ | CD4−CD8− |
|---|---|---|---|---|---|---|---|---|---|---|
Day 30 | ATG-6 | 10.7 (0.3–28.1) | 195.9 (7.8–1488) | 47.6 (0.9–246) | 104.8 (5.2–1273) | 43.7 (0.6–207) | 0.4 (0.0–3.1) | 57.5 (0.7–1091) | 48.3 (1.1–227) | 21.9 (1.6–81.6) |
ATG-10 | 5.9 (0.4–406) | 149.5 (2.1–1433) | 20.1 (0.2–272) | 82.7 (0.1–1283) | 20.0 (0.0–268) | 0.2 (0.0–2.3) | 26.6 (0.1–736) | 19.9 (0.1–260) | 10.9 (0.9–92.7) | |
p value | 0.07 | 0.07 | 0.02 | 0.10 | 0.01 | 0.03 | 0.02 | 0.01 | 0.03 | |
Day 60 | ATG-6 | 15.9 (1.2–140) | 940.8 (60.3–3406) | 140.3 (20.2–1051) | 722.0 (53.0–2666) | 125.8 (17.8–763) | 1.6 (0.1–19.0) | 151.7 (0.4–922) | 111.3 (1.1–481) | 51.5 (1.6–369) |
ATG-10 | 13.1 (0.3–3778) | 691.6 (24.8–6765) | 81.2 (1.8–813) | 533.9 (20.7–5262) | 78.2 (1.6–704) | 0.6 (0.0–94.7) | 159.6 (4.1–2580) | 72.9 (1.7–892) | 22.1 (0.3–703) | |
p value | 0.54 | 0.53 | 0.04 | 0.71 | 0.03 | 0.04 | 0.39 | 0.05 | 0.02 | |
Day 90 | ATG-6 | 15.2 (2.8–102) | 1127.2 (146–2859) | 187.965 (27.2–810) | 784.2 (62.6–2505) | 159.6 (2.3–521) | 1.2 (0.0–19.8) | 195.8 (14.1–732) | 106.9 (36.8–357) | 64.7 (8.0–313) |
ATG-10 | 9.1 (0.3–356) | 885.6 (0.2–5688) | 113.4 (15.7–1162) | 697.3 (0.2–4404) | 109.4 (14.4–911) | 0.7 (0.1–24.2) | 116.7 (0.0–1054) | 62.5 (0.0–496) | 33.5 (0.0–182) | |
p value | 0.27 | 0.26 | 0.09 | 0.78 | 0.14 | 0.23 | 0.29 | 0.02 | 0.04 | |
Day 180 | ATG-6 | 62.0 (2.5–384) | 1423 (333–3543) | 256.2 (67.1–951) | 1092 (171–2995) | 206.5 (58.2–675) | 2.6 (0.8–58.8) | 185.9 (71.6–521) | 224.5 (62.1–362) | 83.9 (23.1–1284) |
ATG-10 | 61.6 (0.4–322) | 1374 (106–4317) | 244.5 (24.5–707) | 1091 (75.9–3714) | 210.0 (22.2–614) | 3.0 (0.1–14.5) | 161.1 (0.3–727) | 131.8 (2.8–343) | 39.8 (5.4–195) | |
p value | 0.68 | 0.39 | 0.49 | 0.99 | 0.73 | 0.68 | 0.32 | 0.06 | 0.01 | |
Day 360 | ATG-6 | 204.5 (23.0–689) | 1688 (803–4680) | 355.9 (178–1061) | 1170 (367.7–4007) | 271.8 (147–512) | 4.6 (0.8–11.7) | 229.3 (96.8–463) | 294.9 (146–1134) | 80.4 (10.0–883) |
ATG-10 | 82.7 (6.2–787) | 1620 (625–4994) | 261.3 (55.1–1579) | 1018 (425–3308) | 224.1 (54.4–1449) | 4.8 (0.3–56.7) | 173.8 (48.8–459) | 200.3 (46.8–571) | 78.2 (8.6–1297) | |
p value | 0.23 | 0.83 | 0.23 | 0.92 | 1.00 | 0.34 | 0.18 | 0.02 | 0.98 |