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Table 1 Anthropometric and biochemical variables in the non-obese and morbidly obese subjects classified according to their insulin resistance levels

From: Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue

 

Non-obese subjects

(N = 15)

MO-low-IR

(N = 15)

MO-high-IR

(N = 15)

Sex (male/female)

4/11

5/10

5/10

Age (years)

40.3 ± 11.8

40.6 ± 11.4

37.2 ± 9.4

Weight (kg)

63.1 ± 8.5

153.6 ± 29.5a

158.7 ± 23.0a

BMI (kg/m2)

22.5 ± 1.7

55.6 ± 7.2a

57.6 ± 4.8a

Waist (cm)

80.0 ± 8.7

140.8 ± 20.3a

147.5 ± 19.6a

Hip (cm)

91.3 ± 7.7

160.1 ± 15.8a

158.1 ± 13.8a

Glucose (mg/dl)

83.1 ± 10.7

91.1 ± 10.5a

107.9 ± 15.8a*

Cholesterol (mg/dl)

192.0 ± 42.6

201.4 ± 40.4

193.5 ± 31.3

Triglycerides (mg/dl)

89.6 ± 44.9

114.7 ± 55.4

163.7 ± 77.8a*

Free fatty acids (mmol/L)

0.305 ± 0.030

0.585 ± 0.066a

0.584 ± 0.042a

Insulin (μIU/ml)

5.9 ± 3.6

12.6 ± 4.1a

39.6 ± 10.4a*

HOMA-IR

1.2 ± 0.72

2.8 ± 0.81a

10.6 ± 2.4a*

Adiponectin (μg/mL)

29.8 ± 18.5

10.9 ± 4.0a

8.0 ± 4.7a

Leptin (ng/mL)

8.2 ± 8.03

77.6 ± 47.8a

59.8 ± 21.5a

  1. The results are given as the mean ± standard deviation
  2. MO-low-IR morbidly obese subjects with low insulin resistance, MO-high-IR morbidly obese subjects with high insulin resistance, BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance index
  3. aP < 0.05 significant differences with respect to the non-obese group
  4. * P < 0.05 significant differences between morbidly obese patients with low and high insulin resistance. All significant differences are adjusted for sex