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Table 3 Study duration effect on LAD lesion severity in high-fat/high-cholesterol fed animals (HFD) at diet-week 22 (n = 6) and 43 (n = 5)

From: Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

Diet week

Non-atherosclerotic intimal lesions

Progressive atherosclerotic lesions

N total

22

5

1

6

43

1

4

5

Total

6

5

 
  1. Graduation of lesions according to Virmani et al. [27]. No statistical significant difference was observed in Fisher’s exact test (significance level p < 0.05)
  2. LAD left anterior descending artery, HFD high-fat/high-cholesterol diet fed animals
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Journal of Translational Medicine

ISSN: 1479-5876

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