Cell line | TP53 genotype | p53 transcript | p53 protein | function | CCI-779 100Â ng/ml |
---|---|---|---|---|---|
UT-SCC-23 | Loss of transcript | - | - | - | 95 |
UM-SCC-11B | missense mutation | + | + | - | 87 |
UD-SCC-5 | missense mutation | + | + | - | 81 |
UD-SCC-4 | delete, fs (stop codon) | + | - | - | 70 |
UM-SCC-22B | missense mutation | + | + | - | 64 |
SCC-9 | delete, fs | + | + (trunc.) | - | 44 |
UM-SCC-17B | wt | + | + | + | 38 |
UM-SCC-74B | wt | + | + | + | 25 |
UT-SCC-15 | Incorrectly spliced transcript, fs | + | + | - | 16 |
UM-SCC-25 | wt | (+) | - | - | 16 |