Figure 2From: Bioenergetic modulation with dichloroacetate reduces the growth of melanoma cells and potentiates their response to BRAFV600E inhibition Effects of DCA on metabolism and ATP levels. A, Relative changes in basal mitochondrial OCR and glycolytic ECAR induced by treatment with 10 mM DCA for 2 hours. B, Relative ATP levels after treatment with DCA (10 or 20 mM) for 24 hours. One-way matched-samples ANOVA was used for statistical analysis and Tukey's HSD test was used to determine statistical significance (*p < 0.05; **p < 0.01).Back to article page