Table 1 Relative changes in mRNA expression of vasoactive, inflammatory, anti-oxidative, and apoptotic mediators in renal parenchyma after IR injury

Endothelin-1

1.00*

2.38 ± 0.48†

1.81 ± 0.34‡

<0.02

Tumor necrosis factor-α

1.00*

2.29 ± 0.25†

1.80 ± 0.20‡

<0.004

Matrix metalloproteinase-9

1.00*

1.48 ± 0.14†

1.19 ± 0.09‡

<0.05

endothelial nitric oxide synthase

1.00*

0.62 ± 0.19†

0.89 ± 0.16‡

<0.05

Interleukin-10

1.00*

2.06 ± 0.37†

2.86 ± 0.50‡

<0.03

Adiponectin

1.00*

0.50 ± 0.13†

0.75 ± 0.13‡

<0.004

NQO1

1.00*

1.89 ± 0.62†

2.76 ± 0.88‡

<0.04

Glutathione reductase

1.00*

1.67 ± 0.25†

2.54 ± 0.64‡

<0.04

Glutathione peroxidase

1.00*

1.83 ± 0.39†

2.82 ± 0.98‡

<0.04

Bcl-2

1.00*

0.74 ± 0.09†

0.94 ± 0.10‡

<0.02

Caspase 3

1.00*

2.01 ± 0.20†

1.53 ± 0.14‡

<0.05