Figure 4
Down-regulation of CDK4 elevated the expression of p21 protein. A.mRNA expression of p21 was inhibited in shRNA-CDK4 cells compared to PLV-Ctr cells and parental A549 cells. B: p21 protein expression was suppressed in shRNA-CDK4 cells compared to PLV-Ctr cells and parental A549 cells. Data were presented as mean ± SD for three independent experiments. *P < 0.05.