Table 1 Human Tumor Antigens
Shared tumor-specific antigens (Cancer - testis antigens) | MAGE, BAGE, GAGE, GnTV, NY-ESO-1, RAGE, TRP2-INT2 |
|---|---|
Antigens from new fusion proteins | bcr-abl, ETV6/AML |
Antigens resulting from mutations | BRAF, CDK4, β-catenin, CASP-8, K-ras, hsp70-2, EF2, TPI, Cdc27, p53 |
Differentiation antigens | Tyrosinase, Melan-A MART1, gp100, gp75TRP1, TRP2, CEA, PSA, PAP, PMSA |
Overexpressed antigens | P53, HER2-neu, PRAME, survivin, telomerase, WT-1 |
Viral antigens | HPV16 E7, EBV |
Other antigens | MUC-1, Idiotype |