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Figure 1 | Journal of Translational Medicine

Figure 1

From: The HIV-1 gp120/V3 modifies the response of uninfected CD4 T cells to antigen presentation: mapping of the specific transcriptional signature

Figure 1

Top molecular and cellular functions identified by IPA. (A) IPA categorized genes exhibited significantly altered expression according to their molecular and cellular function. Green and red letters indicate decreased and increased expression, respectively. The number in the parenthesis indicates the number of altered genes classified to a certain function. (B) The diagram shows significantly overrepresented biofunctions. Corrected p-values, based on the Benjamini-Hochberg method of accounting for multiple testing, was applied by IPA to control the error rate in analysis results. A corrected p-value (FDR) of < 0.05 was considered significant.

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