Table 2 All adverse events observed in the 22 interferon-α 2b-treated patients with melanoma
Grade, n (%) | ||||
|---|---|---|---|---|
Adverse events* | I | II | III | IV |
Hematologic | ||||
Neutropenia | 7 (31) | 5 (23) | 3 (14) | 0 |
Lymphocytopenia | 10 (45) | 5 (23) | 2 (9) | 0 |
Liver function | ||||
AST | 15 (68) | 13 (59) | 10 (45) | 0 |
ALT | 20 (91) | 15 (68) | 12 (54) | 0 |
Nonhematologic | ||||
Fatigue | 17 (77) | 6 (27) | 2 (9) | 0 |
Nausea | 8 (36) | 7 (32) | 2 (9) | 0 |
Vomiting | 5 (22) | 4 (18) | 2 (9) | 0 |
Anorexia | 9 (40) | 3 (14) | 0 | 0 |
Diarrhea | 3 (14) | 0 | 0 | 0 |
Flu-like syndrome† | 17 (77) | 7 (31) | 0 | 0 |
Autoimmunity | 0 | 0 | 0 | 0 |