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Table 3 Association between HU177 concentration and DFS/OS, controlling for tumor thickness and histologic subtype

From: Increased shedding of HU177 correlates with worse prognosis in primary melanoma

Variable

P-value

Hazard ratio (95% CI)

Disease-free survival

  

   Epitope concentrationa

0.049

2.01 (1.002, 4.04)

   Tumor thicknessb

0.065

1.05 (1.00, 1.10)

   Histologyc

0.001

3.66 (1.70, 7.86)

Overall survival

  

   Epitope concentrationa

0.035

2.23 (1.06, 4.70)

   Tumor thicknessb

0.004

1.08 (1.02, 1.13)

   Histologyc

0.363

1.41 (0.67, 2.98)

  1. Abbreviations used: DFS, disease-free survival; OS, overall survival; CI, confidence interval.
  2. a >3.7 ng/ml vs. ≤ 3.7 ng/ml (referent).
  3. b Treated as a continuous variable in the model.
  4. c Nodular/other melanoma vs. superficial spreading melanoma (referent).
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Journal of Translational Medicine

ISSN: 1479-5876

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