Figure 4
In vitro monocytic release of bioactive IL-12p70. Monocytes (1 × 106) purified from the peripheral blood of patients given pegfilgrastim (n = 3) or filgrastim (n = 3) were stimulated with LPS as detailed in the legend to Figure 3B. Supernatants were harvested daily and used to measure IL-12p70 by ELISA. Each point is representative of the mean value of triplicate IL-12p70 measurements.