Table 1 Properties of the Gd-G5-doxorubicin dendrimer
PAMAM dendrimer generation (G) | Terminal amines (#) | Naked dendrimer molecular weight (kDa) | Gd-G5-doxorubicin dendrimer molecular weight (kDa) | Gd-DTPA conjugation (%) | Doxorubicin conjugation (%) | Molar relaxivity (mM-1s-1) |
|---|---|---|---|---|---|---|
G5 | 128 | 29# | 85‡ | 48.1 | 7.8 | 10.1& |