Table 2 Gd-PAMAM dendrimer peak concentrations in orthotopic RG-2 gliomas versus ectopic RG-2 gliomas*
From: Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors
Gd-dendrimer generation (G) | Peak concentration in orthotopic RG-2 gliomas (mM) | Peak concentration time point (min) | Peak concentration in ectopic RG-2 gliomas (mM) | Peak concentration time point (min) |
|---|---|---|---|---|
Gd-G5 | 0.147 | 167 | 0.195 | 149 |
Gd-G6 | 0.106 | 200 | 0.144 | 189 |
Gd-G7 | 0.064 | 75 | 0.084 | 107 |
Gd-G8 | 0.049 | 77 | 0.052 | 81 |