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Figure 1 | Journal of Translational Medicine

Figure 1

From: Progesterone receptor does not improve the performance and test effectiveness of the conventional 3-marker panel, consisting of estrogen receptor, vimentin and carcinoembryonic antigen in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray extension study

Figure 1

H&E and immunohistochemical stains for PR, ER, Vim and CEA identified in endocervical adenocarcinomas (ECA) versus endometrial adenocarcinomas (EMA). A1, B1, C1, D1 and E1 came from one case with ECA, while A2, B2, C2, D2 and E2 came from another case with EMA. (A1) Adenocarcinoma of endocervix, endocervical type, H&E stain. (A2) Adenocarcinoma of endometrium, endometroid type, H&E stain. (B1) Progesterone receptor (PR) IHC score of ECA tumor cells was 0. (B2) Progesterone receptor (PR) IHC score of EMA tumor cells was 12. (C1) Estrogen receptor (PR) IHC score of ECA tumor cells was 0. (C2) Estrogen receptor (PR) IHC score of EMA tumor cells was 12. (D1) Vimentin IHC score of ECA tumor cells was 0. (D2) Vimentin of EMA tumor cells IHC score was12. Internal controls of stroma tissues showed strong positive result in both D1 and D2. (E1) Carcinoembryonic antigen (CEA) IHC score of ECA tumor cells was 12. (E2) Carcinoembryonic antigen (CEA) IHC score of EMA tumor cells was 2. (All were viewed at 400X magnification).

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