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Table 1 Increase in CD4 Cell Counts and CD4:CD8 Ratio After 3 scIL-3 Cycles.

From: CD8 apoptosis may be a predictor of T cell number normalization after immune reconstitution in HIV

scIL-2 Dosage

Change in CD4 Number

Increase in Ratio*

7.5 MIU(n = 4)

863 ± 434

0.88 ± 0.15

1.5 MIU(n = 5)

554 ± 458

0.53 ± 0.09

Control (n = 3)

442 ± 284

0.23 ± 0.14

  1. * Day 65 in treated and week 24 in controls.
  2. All different from each other (p = < 0.01). All patients increased their CD4:CD8 ratio, with the high dose IL-2 patients responding best. There is one missing endpoint in the high dosage at Day 65 and one in the group that received no IL-2 at 24 weeks.
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Journal of Translational Medicine

ISSN: 1479-5876

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