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Table 1 Tumorigenesis in the epigenetic melanoma vaccine model

From: An epigenetic vaccine model active in the prevention and treatment of melanoma

Treatmenta

% AnnexinV+ cells/inocula

Number of mice that developed tumor (total)b

% Tumor-free mice after 40 days

Untreated

~10

32 (33)

3

250 nM TSA (24 h)

~20

9 (10)

10

500 nM TSA (24 h)

~40

7 (10)

30

500 nM TSA (48 h)

~50

19 (48)

61

  1. a TSA-treated (concentrations and length of treatment as indicated) or untreated B16 cells (1 × 105 trypan blue negative adherent cells) were inoculated s.c. in B6 mice. b The total number of mice used per treatment group is shown in parentheses.