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Table 2 Charles River Laboratories study

From: Diagnosis of drug-induced renal tubular toxicity using global gene expression profiles

A_id

C.Dose.Day

H_score

B_class

A_id

C.Dose.Day

H_score

B_class

1

All.006.03

0

-1

65

Pur.075.03

0

-1

2

All.006.03

0

-1

66

Pur.075.03

0

-1

3

All.006.03

0

-1

67

Pur.075.03

0

-1

4

All.006.03

0

-1

68

Pur.075.03

0

-1

5

All.030.03

0

-1

69

Pur.075.07

3

1

6

All.030.03

0

-1

70

Pur.075.07

2

1

7

All.030.03

0

-1

71

Pur.075.07

0

-1

8

All.030.03

0

-1

72

Pur.075.07

0

-1

9

All.100.03

2

1

73

Tob.006.03

0

-1

10

All.100.03

2

1

74

Tob.006.03

0

-1

11

All.100.03

2

1

75

Tob.006.03

0

-1

12

All.100.03

2

1

76

Tob.006.03

0

-1

13

All.100.03

1

1

77

Tob.030.14

1

1

14

All.100.03

1

1

78

Tob.030.14

0

-1

15

All.100.03

1

1

79

Tob.030.14

0

-1

16

All.100.03

1

1

80

Tob.030.14

0

-1

17

All.100.07

2

1

81

Tob.060.03

0

-1

18

All.100.07

2

1

82

Tob.060.03

0

-1

19

All.100.07

1

1

83

Tob.060.03

0

-1

20

All.100.07

1

1

84

Tob.060.03

0

-1

21

All.100.14

2

1

85

Tob.060.14

2

1

22

All.100.14

2

1

86

Tob.060.14

2

1

23

All.100.14

2

1

87

Tob.060.14

2

1

24

All.100.14

1

1

88

Tob.060.14

2

1

25

D-S.750.03

4

1

89

Veh.000.03

1

1

26

D-S.750.03

4

1

90

Veh.000.03

0

-1

27

D-S.750.03

4

1

91

Veh.000.03

0

-1

28

D-S.750.03

0

-1

92

Veh.000.03

0

-1

29

D-S.750.14

2

1

93

Veh.000.03

0

-1

30

D-S.750.14

2

1

94

Veh.000.03

0

-1

31

D-S.750.14

2

1

95

Veh.000.03

0

-1

32

HCB.007.5.03

0

-1

96

Veh.000.03

0

-1

33

HCB.007.5.03

0

-1

97

Veh.000.03

0

-1

34

HCB.007.5.03

0

-1

98

Veh.000.03

0

-1

35

HCB.040.03

1

1

99

Veh.000.03

0

-1

36

HCB.040.03

0

-1

100

Veh.000.03

0

-1

37

HCB.040.03

0

-1

101

Veh.000.03

0

-1

38

HCB.040.14

2

1

102

Veh.000.03

0

-1

39

HCB.040.14

2

1

103

Veh.000.03

0

-1

40

HCB.040.14

2

1

104

Veh.000.03

0

-1

41

HCB.040.14

2

1

105

Veh.000.03

0

-1

42

HCB.100.03

4

1

106

Veh.000.03

0

-1

43

HCB.100.03

4

1

107

Veh.000.03

0

-1

44

HCB.100.03

3

1

108

Veh.000.03

0

-1

45

HCB.100.03

3

1

109

Veh.000.07

1

1

46

Pur.005.03

0

-1

110

Veh.000.07

0

-1

47

Pur.005.03

0

-1

111

Veh.000.07

0

-1

48

Pur.005.03

0

-1

112

Veh.000.07

0

-1

49

Pur.005.03

0

-1

113

Veh.000.07

0

-1

50

Pur.020.03

2

1

114

Veh.000.07

0

-1

51

Pur.020.03

0

-1

115

Veh.000.07

0

-1

52

Pur.020.03

0

-1

116

Veh.000.07

0

-1

53

Pur.020.03

0

-1

117

Veh.000.14

1

1

54

Pur.020.03

0

-1

118

Veh.000.14

1

1

55

Pur.020.03

0

-1

119

Veh.000.14

0

-1

56

Pur.020.03

0

-1

120

Veh.000.14

0

-1

57

Pur.020.03

0

-1

121

Veh.000.14

0

-1

58

Pur.020.07

0

-1

122

Veh.000.14

0

-1

59

Pur.020.07

0

-1

123

Veh.000.14

0

-1

60

Pur.020.07

0

-1

124

Veh.000.14

0

-1

61

Pur.020.14

3

1

125

Veh.000.14

0

-1

62

Pur.020.14

3

1

126

Veh.000.14

0

-1

63

Pur.020.14

3

1

127

Veh.000.14

0

-1

64

Pur.020.14

2

1

128

Veh.000.14

0

-1

  1. Charles River Laboratories samples with histopathological grade and binary class label for SVM classification. The columns are: A_id, the animal identification number; C.Dose.Day, Compound.Dose.Day; H_score, histopathology grade; B_class, the designated SVM class label for binary classification training or testing. The compounds are: All (Allopurinol), D-s (D-serine), HCB (Hexachloro 1,3, butadiene), Pur (Puromycin), Tob (Tobramycin) and Veh (Vehicle control). The designated SVM binary class label was assigned based on the pathology grade. 1–5 labeled as 1, the positive class and 0 labeled as -1, the negative class.