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Table 2 Overview of SNPs of CYP2A13 gene detected in 45 NPC cases

From: Genetic polymorphisms of CYP2A13 and its relationship to nasopharyngeal carcinoma in the Cantonese population

No.

Nucleotide change

Amino acid change

Frequency (%)

Sample distribution

    

No.6,23, 28,38

No.7

No.24

No.25

No.30

No.34

No.36

No.45

1

74 G>A

Arg25Gln

7.8

G/A

    

G/A

 

A/A

2

281 A>G

Intron

3.3

 

A/G

   

A/G

A/G

 

3

396 A>G

Intron

3.3

 

A/G

   

A/G

A/G

 

4

419 G>A

Intron

3.3

 

G/A

   

G/A

G/A

 

5

424 G>A

Intron

3.3

 

G/A

   

G/A

G/A

 

6

441 C>T

Intron

3.3

 

C/T

   

C/T

C/T

 

7

578 C>T

Arg101OPA

1.1

    

C/T

   

8

672 C>A

Intron

3.3

 

C/A

   

C/A

C/A

 

9

742 T>C

Intron

1.1

  

T/C

     

10

760 T>C

Intron

1.1

  

T/C

     

11

761 C>T

Intron

1.1

  

C/T

     

12

867 C>G

Intron

1.1

 

C/G

      

13

1757 A>G

Intron

7.8

A/G

    

A/G

 

G/G

14

1634–1635 ins ACC

133–134 Thr ins

  

/ins ACC

      

15

1801 G>C

Intron

1.1

 

G/C

      

16

1970 A>C

synonym

1

 

A/C

      

17

3375 C>T

Arg257Cys

7.8

C/T

    

C/T

 

T/T

18

5530 T>C

Intron

1.1

 

T/C

      

19

5578 A>C

Intron

1.1

 

A/C

      

20

6958 C>T

Intron

3.3

 

C/T

   

C/T

C/T

 

21

7233 T>G

Intron

12.2

T/G

T/G

 

T/G

 

G/G

T/G

G/G

  1. Notes: The sequence of the complete human CYP2A13 gene described in the GenBank (accession no. NG_000766) was used as a reference sequence, with the A of ATG start codon designated as +1.