Table 3 CD105 as a marker of survival in patients with solid tumors of different histotype.
From: Highlights on endoglin (CD105): from basic findings towards clinical applications in human cancer
Tumor histotype | CD105-MVDa correlation with survival | References |
|---|---|---|
Breast carcinoma | The number of CD105-positive microvessels correlated significantly (p = 0.001) with poor overall survival. | [55] |
Colorectal cancer | Patients with CD105-MVD above the median showed the worst prognosis; similar results were obtained when CD105-MVD was divided in quartiles. | [78] |
Endometrial carcinoma | Patients with the lower quartiles for CD105-MVD showed reduced survival compared to those with the higher quartiles. | [80] |
Non-small cell lung cancer | 5-year survival rate of patients with the lower CD105-MVD was higher compared to that of patients with the higher CD105-MVD. | [84] |
Prostate cancer | Median survival time were shorter for patients with CD105-MVD above the median. | [25] |