Figure 3
From: Systems Medicine: from molecular features and models to the clinic in COPD
The "Disease Interactome". The Interactome (left) represents the complex network of all molecular components (gene products, proteins, metabolites, RNAs etc.) and their interactions. Diseases can be understood as local perturbations. The local neighborhood around genes reported to be associated with COPD (right) is only a very small subset of the full Interactome, yet already shows its enormous complexity.