Figure 5
From: Roles of CXCL5 on migration and invasion of liver cancer cells
Roles of CXCL5 in the metastasis of liver cancer cells. CXCL5 increased LCCs migration and invasion, probably through autocrine and paracrine mechanism. CXCL5-CXCR2-ERK1/2 pathways could play critical and necessary roles in the regulation of LCCs migration. LCCs per se act as the producer and receptor of CXCL5, responsible for the development of inflammatory microenvironment and the promotion of malignancy.