Figure 6
From: In silico modeling predicts drug sensitivity of patient-derived cancer cells
In silico modeling and experimental in vitro data for drug responsiveness to different drugs. This figure demonstrates in silico predictions of sensitivity and in vitro viability in response to treatment of patient-derived GBM cell lines with A, B, bortezomib, C, D, everolimus, E, F, celecoxib, and G, H, pitavastatin. All drugs were tested in vitro at 1 μM for 72 h and viability was assayed using Alamar Blue assay. Cells showing decrease in viability of 20% or greater are considered sensitive to the drug.