Intratumoral delivery of recombinant vaccinia virus encoding for ErbB2/Neu inhibits the growth of salivary gland carcinoma cells

Table 4 T cell immune response of BALB- neu T mice following vaccination with rV- neu T

T cell *in vitro* stimulus	Neu peptide sequence	IL-2 release*		IFN-γ
		rV-*neu* T	V-wt	rV-*neu* T	V-wt
r15.3	TYVPANASL	208	44	519	≤18
r41	DMVLWKDVFRKNNQL	359	43	475	≤18
r98	IAPLRPEQLQVFETL	343	44	510	≤18
r141	LPCHPECQPQNSSET	209	43	555	≤18
r156	GICQPCPINCTHSCV	265	45	365	≤18
r166	VLLFLILVVVVGILI	239	42	585	≤18
GAG		35	41	3	≤18
ConA		1450	2800	2890	3150

*Spleen cells from vaccinated mice were stimulated in vitro with Neu-specific peptides. IL-2 and IFN-γ was quantitated in the supernatant (pg/ml) as a measure of T cell immunoreactivity with specific Neu epitopes. ConcanavalinA (ConA) for global T cell activation and an unrelated gag peptide served as positive and negative control, respectively.

ISSN: 1479-5876