Variables | Day 0 | Day 90 | p-value |
---|---|---|---|
Mean ulcerative wound (grading) | 2.90 ± 1.60 | 2.11 ± 1.64 | < 0.001 |
Painful sensation due to CLI | 92.7% (51) | 19.8% (17) | < 0.001 |
90-day individual clinical outcome | Â | Â | Â |
Gastric ulcer with bleeding | Â | 1.8% (1) | Â |
Status of CLI (90-day end point) | Â | Â | Â |
Amputation due to worsening CLI | Â | 10.9% (6) | Â |
Stationary* | Â | 34.6% (19) | Â |
Greater improvement†|  | 23.6% (13) |  |
Complete healing | Â | 16.4% (9) | Â |
Withdraw | Â | 5.5% (3) | Â |
Sepsis-cause death | Â | 5.5% (3) | Â |
Cardiovascular-caused death | Â | 1.8% (1) | Â |
Cancer-cause death | Â | 1.8% (1) | Â |