In silico approaches for designing highly effective cell penetrating peptides

Table 3 Performance of binary profile-based SVM method

Method	CPPsite-1 dataset					CPPsite-2 dataset					CPPsite-3 dataset
Method	Sn	Sp	AC	MCC	ROC	Sn	Sp	AC	MCC	ROC	Sn	Sp	AC	MCC	ROC
N5	80.08	85.73	82.91	0.66	0.89	86.63	87.17	86.90	0.74	0.90	62.03	65.78	63.90	0.28	0.64
C5	84.60	82.20	83.40	0.67	0.91	91.44	82.35	86.90	0.74	0.95	64.17	67.38	65.78	0.32	0.66
N5-C5	83.19	88.98	86.09	0.72	0.96	91.98	82.35	87.17	0.75	0.95	66.84	66.84	66.84	0.34	0.69
N10	83.95	86.19	85.03	0.70	0.91	89.44	90.34	89.87	0.80	0.95	66.67	63.27	65.05	0.30	0.65
C10	86.55	83.22	84.95	0.70	0.93	87.04	91.10	88.96	0.78	0.95	66.05	61.90	64.08	0.28	0.68
N10-C10	90.60	86.89	88.81	0.78	0.95	93.21	93.84	93.51	0.87	0.96	66.67	64.63	65.70	0.31	0.68

ISSN: 1479-5876