Figure 5

Receiver operating characteristics (ROC) curve analysis using plasma miR-150 and miR-342 for discriminating AML patients. Plasma miR-150 yielded an AUC (the areas under the ROC curve) of 0.835 (95% CI: 0.7119– 0.9581; P<0.0001) with 80% sensitivity and 70% specificity in discriminating AML (A), and plasma miR-342 yielded AUC of 0.8125 (95% CI: 0.6796–0.9454; P=0.0005) with 70% sensitivity and 85% specificity (B) in discriminating AML. Elevated ROC analysis revealed an elevated AUC of 0.860 (95% CI: 0.7819–0.94; P<0.0001) with 73% sensitivity and 78% specificity in discriminating AML (C).