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Table 2 PI3KCA mutations and PTEN loss in Chinese GC

From: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere

Mutation

Assay

Status (%)

PI3KCA (hot spots)

ASPCR

2.7% (4/150)

PTEN loss

IHC

23% (14/61)

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Journal of Translational Medicine

ISSN: 1479-5876

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