Figure 1From: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to TaxotereRepresentative images from PTEN IHC staining. (A). Positive PTEN staining was observed in the cytoplasm and nuclei of the tumor cells (black arrow) and stroma cells (red arrow). (B). Negative PTEN staining in the tumor cells (black arrow) and positive staining in the stroma cells.Back to article page