Table 2 Prevalence of BRAF / NRAS mutations in melanoma tissues
From: Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma
Type of sample | BRAF | NRAS |
|---|---|---|
mutated | mutated | |
(%) | (%) | |
Primary tumour | 223/451 | 46/312 |
(49%) | (15%) | |
Sardinian | 109/178 | 2/105 |
patients | (61%) | (2%) |
non-Sardinian | 114/273 | 44/207 |
patients | (42%) | (21%) |
Metastasis | 153/298 | 34/216 |
(51%) | (16%) | |
Lymph node | 78/151 | 15/102 |
(52%) | (15%) | |
Visceral | 25/47 | 4/30 |
(53%) | (13%) | |
Liver | 16/30 | 3/22 |
(53%) | (14%) | |
Lung | 9/17 | 1/8 |
(53%) | (12%) | |
Skin | 29/54 | 5/38 |
(54%) | (13%) | |
Brain | 21/46 | 10/46 |
(46%) | (22%) | |
Total lesions | 376/749 | 80/528 |
(50%) | (15%) |