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Table 6 ABC score

From: Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism

ABC item

Group

Baseline

4w

8w

16w

24w

Irritability

CBMNC

16.36 ± 9.61

14.00 ± 8.66

9.50 ± 8.81

10.21 ± 9.58

8.14 ± 8.37

Combination

15.00 ± 7.81

11.22 ± 5.76

9.78 ± 4.32

5.67 ± 3.24

4.22 ± 3.19

Control

9.15 ± 5.58

8.31 ± 5.41

8.46 ± 5.41

8.69 ± 5.56

6.92 ± 4.96

Lethargy/Social withdrawal

CBMNC

30.71 ± 6.08

26.86 ± 5.26a

24.07 ± 7.08a

23.86 ± 8.62a

24.14 ± 9.65a

Combination

31.00 ± 6.98

25.78 ± 6.50a

22.67 ± 5.27a

21.11 ± 5.82a

*16.00 ± 7.92ab

Control

35.08 ± 4.96

34.31 ± 5.14

33.92 ± 4.73

32.46 ± 5.55

*30.54 ± 5.03

Stereotypic behavior

CBMNC

29.43 ± 9.77

*22.43 ± 8.98

*18.86 ± 10.52

*18.00 ± 10.86

*17.07 ± 9.93

Combination

28.33 ± 8.47

20.78 ± 8.81

17.22 ± 7.12

13.22 ± 6.78

*9.33 ± 5.81ab

Control

22.77 ± 6.86

20.85 ± 6.63

21.08 ± 4.82

18.38 ± 5.58

17.31 ± 4.05

Hyperactivity

CBMNC

11.86 ± 4.55a

10.07 ± 4.63

7.57 ± 4.83

7.29 ± 5.27

6.86 ± 5.26

Combination

11.89 ± 6.88a

9.33 ± 5.87

7.22 ± 5.19

5.89 ± 3.37

4.67 ± 3.74

Control

6.08 ± 3.15

6.31 ± 2.81

6.46 ± 3.38

6.15 ± 3.39

5.08 ± 2.40

Inappropriate speech

CBMNC

5.71 ± 4.30a

3.79 ± 3.29

3.43 ± 3.34

2.93 ± 2.87

2.14 ± 2.32

Combination

5.56 ± 2.83a

4.56 ± 2.92

3.11 ± 1.62

3.22 ± 2.44

2.56 ± 2.19

Control

2.38 ± 2.10

2.69 ± 2.21

3.00 ± 2.27

2.92 ± 2.56

2.46 ± 2.63

Total score

CBMNC

94.07 ± 21.98

77.14 ± 22.4

*63.43 ± 29.93

*62.29 ± 33.98

*58.36 ± 31.73a

 

Combination

91.78 ± 25.92

71.67 ± 22.57

60.00 ± 18.94

49.11 ± 14.61

*36.78 ± 16.95ab

 

Control

75.46 ± 12.05

72.46 ± 12.95

72.92 ± 11.43

68.62 ± 12.58

*62.31 ± 11.3

  1. Note: *Aberrant behavioral scores at different follow-up time-points compared with baseline scores in each group (p < 0.05). aAberrant behavioral scores of the Combination or CBMNC group compared with the Control group (p < 0.05). bComparison of aberrant behavioral scores of the Combination group with the CBMNC group (p < 0.05).