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Table 1 Univariate and multivariate analysis for overall survival

From: MicroRNA-503 inhibits the G1/S transition by downregulating cyclin D3 and E2F3 in hepatocellular carcinoma

Clinical variables

HR (95% CI)

P-value

Univariate analysis

  

Age

1.021(0.823-1.346)

0.886

Sex

0.953(0.545-1.875)

0.754

HBV

1.067(0.513-2.184)

0.864

Cirrhosis

1.652(0.738-3.678)

0.237

Tumor size

1.542(1.136-2.246)

0.087

Tumor number

2.421(1.546-4.439)

0.246

TNM stage

2.876(1.873-4.786)

0.002

Histology grade

1.724(1.120-2.863)

0.027

PVTT

3.539(2.238-7.731)

0.017

AFP

2.535(1.347-5.042)

0.027

miR-503 expression

2.942(1.857-4.974)

0.001

Multivariate analysis

  

TNM stage

2.054(1.573-4.853)

0.015

Histology grade

1.431(0.690-2.968)

0.336

PVTT

0.549(0.242-1.246)

0.152

AFP

1.147(0.575-2.288)

0.697

miR-503 expression

2.461(1.106-4.623)

0.005

  1. HR Hazard ratios, CI confidence interval, HBV Hepatitis B virus, TNM tumor-node-metastasis, PVTT portal vein tumor thrombi, AFP Alpha-fetoprotein, Boldface P values indicate statistical significant.