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Table 3 Genotype and allele distribution of DEFB1 and CD14 in control subjects and periodontitis patients

From: Clinical application of human β-defensin and CD14 gene polymorphism in evaluating the status of chronic inflammation

Genotypes

CP Patients n=44 (%)

Healthy subjects n=108 (%)

CP versus Healthy subjects

Alleles

CP patient n=88 (%)

Healthy subjects n=216 (%)

CP versus Healthy subjects

   

OR (95% CI)

p values

   

OR (95% CI)

p values

DEFB1

         

A/A

30 (69)

38 (35)

3.9474 (1.8697-8.3339)

<0.0002*

A

65 (74)

88 (41)

4.1107 (2.3775-7.1073)

<0.0001*

G/G

9 (20)

58 (54)

  

G

23 (26)

128 (59)

  

G/A

5 (11)

12 (11)

       

CD14

         

T/T

19 (43)

28 (26)

2.1714 (1.0406-4.5311)

<0.0368*

T

59 (67)

119 (55)

1.6584 (0.9868-2.7869)

<0.05501

C/C

4 (10)

17 (16)

  

C

29 (33)

97 (45)

  

C/T

21 (47)

63 (58)

       
  1. DEFB1: G/G+G/A versus A/A; CD14: C/C+C/T versus T/T; OR, odds ratio; CI, confidence interval
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Journal of Translational Medicine

ISSN: 1479-5876

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