Figure 7From: Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivoAnti-PLSCR1 represses tumorigenesis by inhibiting EGFR-related downstream signaling. (A) The expression of EGFR, Src, PLSCR1, Shc, and Erks was evaluated with western blotting after the cells were treated with NP1 or isotype-control IgG. (B) Phosphorylation of Src, Shc, and Erks decreased following NP1 treatment in HT29 cells.Back to article page