From: Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients
Variable | n. patients | % |
---|---|---|
Age, years | ||
Median | 52 | |
Range | 29-83 | |
Gender | ||
Male | 28 | 62.2 |
Female | 17 | 37.8 |
Localization of primary tumor | ||
extremities | 16 | 35.6 |
trunk | 24 | 53.3 |
head & neck | 2 | 4.4 |
NA1 | 3 | 6.7 |
Breslow thickness of primary tumor | ||
≤2.0 mm | 13 | 28.9 |
>2.0 mm | 25 | 55.6 |
NA | 7 | 15.6 |
Clark level of primary tumor | ||
1-3 | 13 | 28.9 |
4-5 | 26 | 57.8 |
NA | 6 | 13.3 |
Ulceration of primary tumor | ||
No | 10 | 22.2 |
Yes | 33 | 73.3 |
NA | 2 | 4.4 |
N. lymph nodes involved | ||
1 | 9 | 20 |
>1 | 35 | 77.8 |
NA | 1 | 2.2 |
LDH2 | ||
Low3 | 31 | 68.9 |
High | 11 | 24.4 |
NA | 3 | 6.7 |
BRAFV600E | ||
mutated | 25 | 55.6 |
wild-type | 15 | 33.3 |
NA | 5 | 11.1 |
LINE-1 4 | ||
hypomethylated | 22 | 49 |
hypermethylated | 23 | 51 |