Figure 5
From: Combination of cilostazol and clopidogrel attenuates Rat critical limb ischemia
Protein and mRNA expressions of apoptotic biomarkers in ischemic quadriceps by day 21 following CLI procedure (n = 8). A and B) showing mRNA expression of caspase 3 and Bax, respectively. for (A) and (B), * vs. other groups with different symbols, p < 0.0001. C) mitochondrial protein expression of Bax. * vs. other groups with different symbols, p < 0.008. D) mRNA expression of Bcl-2. * vs. other groups with different symbols, p < 0.0001. Statistical analysis in each group by ANOVA followed by Bonferroni multiple comparison post hoc test. CLI = critical limb ischemia; Cil = cilostazol; Clo = clopidogrel.