Figure 1

Endotoxemia led to rapid increases in (A) TNF-α (** p < 0.001 vs. placebo, peak 2 hours) and (B) IL-6 (** p < 0.001 vs. placebo, peak 2 hours). Endotoxemia also increased (C) white blood cell counts (*p < 0.05 vs. placebo, peak 4 hours) and (D) CRP levels (*p < 0.001 vs. placebo, peak 24 hours). Data presented as mean ± SEM (n = 10).