Figure 2

Representative examples of HER2 and TopoIIa protein expression and corresponding gene status. A-D: immunohistochemistry at a magnification of 100Χ (A: HER2 3+, B: HER2 0, C: TopoIIa positive and D: TopoIIa negative). E-H: CISH at a magnification of 600Χ (E: HER2 positive/amplified, F: HER2 negative/diploid, G: TOP2A positive and H: TOP2A negative).