Skip to main content

Articles

Page 7 of 105

  1. The development of Bruton’s tyrosine kinase inhibitors (BTKi) for the treatment of chronic lymphocytic leukaemia (CLL) has provided a highly effective and relatively non-toxic alternative to conventional chemo...

    Authors: Joanne E. Davis, Chia Sharpe, Kylie Mason, Constantine S. Tam, Rachel M. Koldej and David S. Ritchie
    Citation: Journal of Translational Medicine 2021 19:473
  2. There is accumulating evidence of endothelial dysfunction, muscle and cerebral hypoperfusion in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In this paper we deduce the pathomechanisms resultin...

    Authors: Klaus J. Wirth, Carmen Scheibenbogen and Friedemann Paul
    Citation: Journal of Translational Medicine 2021 19:471

    The Correction to this article has been published in Journal of Translational Medicine 2022 20:25

    The Letter to the Editor to this article has been published in Journal of Translational Medicine 2022 20:40

  3. Diabetes mellitus (DM), a most common chronic disease, is featured with impaired endothelial function and bioavailability of nitric oxide (NO), while E3 ubiquitin ligase appears to alleviate endothelial dysfun...

    Authors: Qingsong Jin, Liangyan Lin, Tiantian Zhao, Xiaoyan Yao, Yaqin Teng, Dongdong Zhang, Yongjun Jin and Meizi Yang
    Citation: Journal of Translational Medicine 2021 19:469
  4. Long non-coding RNAs (lncRNAs), functioning as competing endogenous RNAs (ceRNAs), have been reported to play important roles in the pathogenesis of autoimmune diseases. However, little is known about the regu...

    Authors: Shuang Li, Xu Wang, Tianfeng Wang, Huixue Zhang, Xiaoyu Lu, Li Liu, Lifang Li, Chunrui Bo, Xiaotong Kong, Si Xu, Shangwei Ning, Jianjian Wang and Lihua Wang
    Citation: Journal of Translational Medicine 2021 19:468
  5. Breast cancer remains one of the most dreadful female malignancies globally, in which cancer stem cells (CSCs) play crucial functions. Circular RNAs have drawn great attention in cancer research area and propo...

    Authors: Yi-Ping Liu, Jin-Yu Heng, Xin-Yu Zhao and En-You Li
    Citation: Journal of Translational Medicine 2021 19:467
  6. Despite the benefits of extracorporeal cardiopulmonary resuscitation (ECPR) in cohorts of selected patients with cardiac arrest (CA), extracorporeal membrane oxygenation (ECMO) includes an artificial oxygenati...

    Authors: Tai Yin, Lance B. Becker, Rishabh C. Choudhary, Ryosuke Takegawa, Muhammad Shoaib, Koichiro Shinozaki, Yusuke Endo, Koichiro Homma, Daniel M. Rolston, Shuhei Eguchi, Tadashi Ariyoshi, Asami Matsumoto, Kentaro Oka, Motomichi Takahashi, Tomoaki Aoki, Santiago J. Miyara…
    Citation: Journal of Translational Medicine 2021 19:462
  7. Abdominal aortic aneurysm (AAA), an irreversible cardiovascular disease prevalent in the artery, causes the increase of the aneurysm diameter over time, and is a fatal phenomenon inducing sidewall rupture. Lon...

    Authors: Tianming Le, Xin He, Jianhua Huang, Shuai Liu, Yang Bai and Kemin Wu
    Citation: Journal of Translational Medicine 2021 19:466
  8. Despite much evidence supporting the monitoring of the divergence of transcutaneous partial pressure of carbon dioxide (tcPCO2) from arterial partial pressure carbon dioxide (artPCO2) as an indicator of the shock...

    Authors: Yusuke Endo, Taku Hirokawa, Taku Miyasho, Ryosuke Takegawa, Koichiro Shinozaki, Daniel M. Rolston, Lance B. Becker and Kei Hayashida
    Citation: Journal of Translational Medicine 2021 19:390
  9. Toll-like receptors (TLRs) on neutrophils play a crucial role in detecting pathogens and organ/tissue injury in acute-on-chronic liver failure (ACLF). However, little is known about the exact mechanisms and po...

    Authors: Yi Zhang, Wei Wu, Yijie Wang, Lingjia Tong, Meng Hong, Qi Xia and Zhi Chen
    Citation: Journal of Translational Medicine 2021 19:465
  10. Intestinal ischemia/reperfusion (I/R) injury commonly occurs during perioperative periods, resulting in high morbidity and mortality on a global scale. Dexmedetomidine (Dex) is a selective α2-agonist that is f...

    Authors: Qin Zhang, Xiao-Ming Liu, Qian Hu, Zheng-Ren Liu, Zhi-Yi Liu, Huai-Gen Zhang, Yuan-Lu Huang, Qiu-Hong Chen, Wen-Xiang Wang and Xue-Kang Zhang
    Citation: Journal of Translational Medicine 2021 19:463
  11. Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease which involves multiple body systems (e.g., immune, nervous, digestive, circulatory) and research domains (e.g., immunology...

    Authors: Ravi Mathur, Megan U. Carnes, Alexander Harding, Amy Moore, Ian Thomas, Alex Giarrocco, Michael Long, Marcia Underwood, Christopher Townsend, Roman Ruiz-Esparza, Quinn Barnette, Linda Morris Brown and Matthew Schu
    Citation: Journal of Translational Medicine 2021 19:461
  12. Sarcoidosis is an inflammatory disease characterized by the formation of granulomas, which involve the heart in up to 25% of patients. Cardiac sarcoidosis can lead to life threatening arrhythmias and heart fai...

    Authors: Jordana Kron, Thomas Crawford, Virginia Mihalick, Frank Bogun, Jennifer H. Jordan, Todd Koelling, Huzaefah Syed, Aamer Syed, Thomas Iden, Kelly Polly, Emily Federmann, Kirsta Bray, Sangeeta Lathkar-Pradhan, Shilpa Jasti, Lynda Rosenfeld, David Birnie…
    Citation: Journal of Translational Medicine 2021 19:460
  13. Adoptive transfer of chimeric antigen receptor (CAR)-engineered T cells combined with checkpoint inhibition may prevent T cell exhaustion and improve clinical outcomes. However, the approach is limited by cumu...

    Authors: Zhifen Yang, Lingyu Li, Ahu Turkoz, Pohan Chen, Rona Harari-Steinfeld, Maggie Bobbin, Ofir Stefanson, Hana Choi, Violena Pietrobon, Bennett Alphson, Angshumala Goswami, Vitaly Balan, Alper Kearney, Dharmesh Patel, Jin Yang, Damla Inel…
    Citation: Journal of Translational Medicine 2021 19:459
  14. Induction of long-term synaptic depression (LTD) is proposed as a treatment mechanism for chronic pain but remains untested in clinical populations. Two interlinked studies; (1) A patient-assessor blinded, ran...

    Authors: Selina Johnson, Anne Marshall, Dyfrig Hughes, Emily Holmes, Florian Henrich, Turo Nurmikko, Manohar Sharma, Bernhard Frank, Paul Bassett, Andrew Marshall, Walter Magerl and Andreas Goebel
    Citation: Journal of Translational Medicine 2021 19:458
  15. Periodontitis is a chronic inflammatory disease that leads to the destruction of both soft and hard periodontal tissues. Complete periodontal regeneration in clinics using the currently available treatment app...

    Authors: Hongbing Lin, Huishan Chen, Xuetao Zhao, Zhen Chen, Peipei Zhang, Yue Tian, Yawei Wang, Tong Ding, Lijing Wang and Yuqin Shen
    Citation: Journal of Translational Medicine 2021 19:456
  16. Circular RNAs (circRNAs) are pivotal regulators of various human cancers and circ-ERBB2 is abnormally expressed in breast cancer cells. However, the role and mechanism of circ-ERBB2 in HER2-positive breast can...

    Authors: Jin-xiu Zhong, Yun-yuan Kong, Rong-guang Luo, Guo-jin Xia, Wen-xing He, Xue-zhong Chen, Wei-wei Tan, Qing-jie Chen, Yu-yin Huang and Yan-xing Guan
    Citation: Journal of Translational Medicine 2021 19:455
  17. Ovarian cancer was one of the leading causes of female deaths. Patients with OC were essentially incurable and portends a poor prognosis, presumably because of profound genetic heterogeneity limiting reproduci...

    Authors: Hongyu Zhao, Yu Teng, Wende Hao, Jie Li, Zhefeng Li, Qi Chen, Chenghong Yin and Wentao Yue
    Citation: Journal of Translational Medicine 2021 19:454
  18. HIV-1 reservoirs persist in the presence of combined antiretroviral therapy (cART). However, cART has transformed HIV-1 infection into a chronic disease marked by control of HIV-1 viral load and mortality redu...

    Authors: Matthew Weichseldorfer, Yvonne Affram, Alonso Heredia, Zahra Rikhtegaran-Tehrani, Mohammad M. Sajadi, Sumiko P. Williams, Yutaka Tagaya, Francesca Benedetti, Habib O. Ramadhani, Frank Denaro, Arshi Munawwar, Joseph Bryant, Davide Zella, Marvin Reitz, Fabio Romerio and Olga S. Latinovic
    Citation: Journal of Translational Medicine 2021 19:453
  19. The discovery of the Cystic fibrosis (CF) gene in 1989 has paved the way for incredible progress in treating the disease such that the mean survival age of individuals living with CF is now ~58 years in Canada...

    Authors: Jin-A Lee, Alex Cho, Elena N. Huang, Yiming Xu, Henry Quach, Jim Hu and Amy P. Wong
    Citation: Journal of Translational Medicine 2021 19:452
  20. Hypertrophic scar (HTS) is a fibrotic disorder of skins and may have repercussions on the appearance as well as functions of patients. Recent studies related have shown that competitive endogenous RNA (ceRNA) ...

    Authors: Zewei Zhang, Xin Huang, Jiahao Yang, Shuchen Gu, Yixuan Zhao, Yunhan Liu, Yimin Khoong, Shuqi Wang, Shenying Luo, Tao Zan and Guangshuai Li
    Citation: Journal of Translational Medicine 2021 19:451

    The Correction to this article has been published in Journal of Translational Medicine 2022 20:35

  21. Osteosarcoma (OS) is the most frequent primary bone cancer, affecting mostly children and adolescents. Although much progress has been made throughout the years towards treating primary OS, the 5-year survival...

    Authors: Taiana Campos Leite, Rebecca Jean Watters, Kurt Richard Weiss and Giuseppe Intini
    Citation: Journal of Translational Medicine 2021 19:450
  22. Cancer is one of the most serious diseases threatening human health. Cancer immunotherapy represents the most promising treatment strategy due to its high efficacy and selectivity and lower side effects compar...

    Authors: Shihu Jiao, Quan Zou, Huannan Guo and Lei Shi
    Citation: Journal of Translational Medicine 2021 19:449
  23. Established clinical assessments for detecting dementia risk often require time, cost, and face-to-face meetings. We aimed to develop a Simplified Telephone Assessment for Dementia risk (STAD) (a new screening...

    Authors: Keitaro Makino, Sangyoon Lee, Seongryu Bae, Ippei Chiba, Kenji Harada, Osamu Katayama, Yohei Shinkai and Hiroyuki Shimada
    Citation: Journal of Translational Medicine 2021 19:448
  24. Ovarian cancer, a highly metastatic malignancy, has benefited tremendously from advances in modern human genomics. However, the genomic variations related to the metastasis remains unclear.

    Authors: Mengyao Xu, Shan Huang, Jiahui Chen, Wanxue Xu, Rong Xiang, Yongjun Piao and Shuangtao Zhao
    Citation: Journal of Translational Medicine 2021 19:447
  25. Young patients with colorectal cancer (CRC) exhibit poor prognoses compared to older patients due to the difficulty in early diagnosis and treatment. However, the underlying molecular characteristics are still...

    Authors: Tae Won Kim, Hye Kyung Hong, Chung Lee, Sunmin Kim, Woo Yong Lee, Seong Hyeon Yun, Hee Cheol Kim, Jung Wook Huh, Yoon Ah Park, Je-Gun Joung, Woong-Yang Park and Yong Beom Cho
    Citation: Journal of Translational Medicine 2021 19:446
  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Hongyu Zhang, Fenzan Wu, Xiaoxia Kong, Jie Yang, Huijun Chen, Liancheng Deng, Yi Cheng, Libing Ye, Sipin Zhu, Xie Zhang, Zhouguang Wang, Hongxue Shi, Xiaobing Fu, Xiaokun Li, Huazi Xu, Li Lin…
    Citation: Journal of Translational Medicine 2021 19:445

    The original article was published in Journal of Translational Medicine 2014 12:130

  27. High-grade glioma has a poor prognosis, and GSCs can have pivotal roles in glioma pathology. This study investigated GSC exosome-containing circRNA mechanisms affecting the malignant progression of glioma.

    Authors: Guowei Li and Qing Lan
    Citation: Journal of Translational Medicine 2021 19:444
  28. This study aimed to evaluate the utility of radiomics-based machine learning analysis with multiparametric DWI and to compare the diagnostic performance of radiomics features and mean diffusion metrics in the ...

    Authors: Kun Sun, Zhicheng Jiao, Hong Zhu, Weimin Chai, Xu Yan, Caixia Fu, Jie-Zhi Cheng, Fuhua Yan and Dinggang Shen
    Citation: Journal of Translational Medicine 2021 19:443
  29. Authors: Francesco Perrone, Maria Carmela Piccirillo, Paolo Antonio Ascierto, Carlo Salvarani, Roberto Parrella, Anna Maria Marata, Patrizia Popoli, Laurenzia Ferraris, Massimiliano M. Marrocco-Trischitta, Diego Ripamonti, Francesca Binda, Paolo Bonfanti, Nicola Squillace, Francesco Castelli, Maria Lorenza Muiesan, Miriam Lichtner…
    Citation: Journal of Translational Medicine 2021 19:442

    The original article was published in Journal of Translational Medicine 2020 18:405

  30. Bitter taste-sensing type 2 receptors (TAS2Rs or T2Rs), belonging to the subgroup of family A G-protein coupled receptors (GPCRs), are of crucial importance in the perception of bitterness. Although in the fir...

    Authors: Kamila Tuzim and Agnieszka Korolczuk
    Citation: Journal of Translational Medicine 2021 19:440

    The Correction to this article has been published in Journal of Translational Medicine 2021 19:478

  31. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yuan Chi, Zheng Gong, He Xin, Ziwen Wang and Zhaoyu Liu
    Citation: Journal of Translational Medicine 2021 19:438

    The original article was published in Journal of Translational Medicine 2020 18:126

  32. Radiotherapy (RT) still represents a mainstay of treatment in clinical oncology. Traditionally, the effectiveness of radiotherapy has been attributed to the killing potential of ionizing radiation (IR) over ma...

    Authors: Turid Hellevik, Rodrigo Berzaghi, Kristin Lode, Ashraful Islam and Inigo Martinez-Zubiaurre
    Citation: Journal of Translational Medicine 2021 19:437
  33. The number of older people is estimated to increase from 524 million in 2010 to 1.5 billion in 2050. The factors and models of human longevity and successful aging are questions that have intrigued individuals...

    Authors: Shihui Fu, Ping Ping, Yulong Li, Bo Li, Yali Zhao, Yao Yao and Pei Zhang
    Citation: Journal of Translational Medicine 2021 19:436
  34. Authors: Dan Wang, Weitang Yuan, Yaping Wang, Qian Wu, Li Yang, Feng Li, Xinfeng Chen, Zhen Zhang, Weina Yu, Nomathamsanqa Resegofetse Maimela, Ling Cao, Dong Wang, Junxia Wang, Zhenqiang Sun, Jinbo Liu and Yi Zhang
    Citation: Journal of Translational Medicine 2021 19:435

    The original article was published in Journal of Translational Medicine 2019 17:253

  35. Authors: Qilu Wei, Ning Kong, Xiaohui Liu, Run Tian, Ming Jiao, Yiyang Li, Huanshuai Guan, Kunzheng Wang and Pei Yang
    Citation: Journal of Translational Medicine 2021 19:434

    The original article was published in Journal of Translational Medicine 2021 19:157

  36. Colorectal carcinoma (CRC) harboring oncogenic fusions has been reported to be highly enriched in mismatch repair deficient (dMMR) tumors with MLH1 hypermethylation (MLH1me+) and wild-type BRAF and RAS. In this s...

    Authors: Jing Wang, Ruiyu Li, Junjie Li, Yuting Yi, Xiaoding Liu, Jingci Chen, Hui Zhang, Junliang Lu, Cami Li, Huanwen Wu and Zhiyong Liang
    Citation: Journal of Translational Medicine 2021 19:433
  37. Gastric cancer (GC) is the fifth most commonly diagnosed cancer worldwide. Due to the dismal prognosis, identifying novel therapeutic targets in GC is urgently needed. Evidences have shown that miRNAs played c...

    Authors: Yixun Lu, Benlong Zhang, Baohua Wang, Di Wu, Chuang Wang, Yunhe Gao, Wenquan Liang, Hongqing Xi, Xinxin Wang and Lin Chen
    Citation: Journal of Translational Medicine 2021 19:432
  38. High morbidity and mortality due to carbapenem-resistant Gram-negative bacilli (CR-GNB) has led to the resurgence of polymyxin B (PMB) use in the last decade. The aim of our multicenter, real-world study was t...

    Authors: Xiaojuan Zhang, Shaoyan Qi, Xiaoguang Duan, Bing Han, Shuguang Zhang, Shaohua Liu, Haixu Wang, Haibo Zhang and Tongwen Sun
    Citation: Journal of Translational Medicine 2021 19:431
  39. Central itch syndrome has been previously described in conditions such as stroke. The neurophysiology of central itch syndrome has been investigated in non-human primates but remains incompletely understood.

    Authors: Luciano Furlanetti, Harutomo Hasegawa, Natasha Hulse, Rachael Morris-Jones and Keyoumars Ashkan
    Citation: Journal of Translational Medicine 2021 19:430
  40. Colorectal cancer is one of the most common malignancy in the world. It has been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis and tumor progression. There is an urgent n...

    Authors: Yifan Li, Jing Xun, Botao Wang, Yuan Ma, Lanqiu Zhang, Lei Yang, Ruifang Gao, Jun Guan, Tianyu Liu, Hejun Gao, Ximo Wang and Qi Zhang
    Citation: Journal of Translational Medicine 2021 19:429
  41. In the ovarian follicle, the Theca Cells (TCs) have two main functions: preserving morphological integrity and, importantly, secreting steroid androgen hormones. TCs express the essential enzyme 17α-hydroxylas...

    Authors: Christian Secchi, Martina Belli, Tracy N. H. Harrison, Joseph Swift, CheMyong Ko, Antoni J. Duleba, Dwayne Stupack, R. Jeffrey Chang and Shunichi Shimasaki
    Citation: Journal of Translational Medicine 2021 19:428
  42. The association between exposure to air pollution and sudden sensorineural hearing loss (SSNHL) has not been extensively discussed in the literature. Therefore, we conducted this nationwide study to evaluate t...

    Authors: Stella Chin-Shaw Tsai, Yi-Chao Hsu, Jung-Nien Lai, Ruey-Hwang Chou, Hueng-Chuen Fan, Frank Cheau-Feng Lin, Ruihong Zhang, Cheng-Li Lin and Kuang-Hsi Chang
    Citation: Journal of Translational Medicine 2021 19:424
  43. This research aimed to investigate the expression and function of FAM83A in the proliferation and metastasis in head and neck squamous cell carcinoma (HNSCC). FAM83A mRNA and protein expressions in HNSCC were ...

    Authors: Huan Ji, Haiyang Song, Zeyu Wang, Pengfei Jiao, Jiani Xu, Xuan Li, Hongming Du, Heming Wu and Yi Zhong
    Citation: Journal of Translational Medicine 2021 19:423

Annual Journal Metrics