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  1. Authors: JCA Broen, P Dieude, M C Vonk, L Beretta, B Rueda, A Herrick, J Worthington, N Hunzelmann, G Riemekasten, H Kiener, R Scorza, C P Simeon, V Fonollosa, P Carreira, N Ortego-Centeno, M A Gonzalez-Gay…

    Citation: Journal of Translational Medicine 2010 8(Suppl 1):P47

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  2. Authors: JCA Broen, P Gourh, M C Vonk, L Beretta, F Niederer, B Rueda, L Geurts-van Bon, C Brouwer, R Hesselstrand, A Herrick, J Worthington, N Hunzelman, C Denton, C Fonseca, G Riemekasten, H Kiener…

    Citation: Journal of Translational Medicine 2010 8(Suppl 1):P46

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  3. Authors: L Bossini-Castillo, JCA Broen, C P Simeon, L Beretta, M C Vonk, N Ortego-Centeno, G Espinosa, P Carreira, M T Camps, N Navarrete, M F González-Escribano, E Vicente-Rabaneda, L Rodríguez, C Tolosa, J A Román-Ivorra, I Gómez-Gracia…

    Citation: Journal of Translational Medicine 2010 8(Suppl 1):P5

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  4. Authors: L M Diaz-Gallo, L Espino-Paisán, K Fransen, M Gómez-García, S van Sommeren, C Cardeña, L Rodrigo, J L Mendoza, C Taxonera, A Nieto, G Alcain, I Cueto, M A López-Nevot, N Bottini, M L Barclay, J B Crusius…

    Citation: Journal of Translational Medicine 2010 8(Suppl 1):P2

    Content type: Poster presentation

    Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  5. Authors: O Gorlova, J M Martin, B Rueda, BPC Koeleman, J Ying, M Teruel, L M Diaz-Gallo, J C Broen, M C Vonk, C P Simeon, B Z Alizadeh, MJH Coenen, A E Voskuyl, A J Schuerwegh, PLCM van Riel, M Vanthuyne…

    Citation: Journal of Translational Medicine 2010 8(Suppl 1):O1

    Content type: Oral presentation

    Published on:

    This article is part of a Supplement: Volume 8 Supplement 1

  6. Most colorectal carcinomas are driven by an activation of the canonical Wnt signalling pathway, which promotes the expression of multiple target genes mediating proliferation inavasion and invasion. Upon activ...

    Authors: Lydia Kriegl, David Horst, Jana A Reiche, Jutta Engel, Thomas Kirchner and Andreas Jung

    Citation: Journal of Translational Medicine 2010 8:123

    Content type: Research

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  7. To evaluate fluorescence cystoscopy with hexaminolevulinate (HAL) in the early detection of dysplasia (DYS) and carcinoma in situ (CIS) in select high risk patients.

    Authors: Salvatore Blanco, Marco Raber, Biagio Eugenio Leone, Luca Nespoli and Marco Grasso

    Citation: Journal of Translational Medicine 2010 8:122

    Content type: Methodology

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  8. Recent preclinical adoptive immunotherapy studies in murine models prompt to employ "proper" rather than "as many as possible" antigen-specific T cells to gain better therapeutic results. Ideally, "proper" T c...

    Authors: Anna Merlo, Riccardo Turrini, Cristina Trento, Paola Zanovello, Riccardo Dolcetti and Antonio Rosato

    Citation: Journal of Translational Medicine 2010 8:121

    Content type: Research

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  9. Growth hormone (GH) is an essential regulator of intrahepatic lipid metabolism by activating multiple complex hepatic signaling cascades. Here, we examined whether chronic exogenous GH administration (via gene...

    Authors: Ying Qin and Ya-ping Tian

    Citation: Journal of Translational Medicine 2010 8:120

    Content type: Research

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  10. Culturing otospheres from dissociated organ of Corti is an appropriate starting point aiming at the development of cell therapy for hair cell loss. Although guinea pigs have been widely used as an excellent ex...

    Authors: Jeanne Oiticica, Luiz Carlos M Barboza-Junior, Ana Carla Batissoco, Karina Lezirovitz, Regina C Mingroni-Netto, Luciana A Haddad and Ricardo F Bento

    Citation: Journal of Translational Medicine 2010 8:119

    Content type: Research

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  11. Zinc is important. It is the second most abundant trace metal with 2-4 grams in humans. It is an essential trace element, critical for cell growth, development and differentiation, DNA synthesis, RNA transcrip...

    Authors: Erica John, Thomas C Laskow, William J Buchser, Bruce R Pitt, Per H Basse, Lisa H Butterfield, Pawel Kalinski and Michael T Lotze

    Citation: Journal of Translational Medicine 2010 8:118

    Content type: Review

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  12. Recent years have seen a growing interest in insulin-like growth factor 1 receptor (IGF1R) in medical oncology. Interesting data have been reported also on IGF1r in gastrointestinal stromal tumors (GISTs) espe...

    Authors: Maria A Pantaleo, Annalisa Astolfi, Margherita Nannini and Guido Biasco

    Citation: Journal of Translational Medicine 2010 8:117

    Content type: Commentary

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  13. DNA vaccines represent an attractive approach for cancer treatment by inducing active T cell and B cell immune responses to tumor antigens. Previous studies have shown that interleukin-13 receptor α2 chain (IL...

    Authors: Hideyuki Nakashima, Toshio Fujisawa, Syed R Husain and Raj K Puri

    Citation: Journal of Translational Medicine 2010 8:116

    Content type: Research

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  14. Pegylated granulocyte colony-stimulating factor (G-CSF; pegfilgrastim) is a longer-acting form of G-CSF, whose effects on dendritic cell (DC) and regulatory T cell (Treg) mobilization, and on the in vivo and ex v...

    Authors: Giuseppina Bonanno, Annabella Procoli, Andrea Mariotti, Maria Corallo, Alessandro Perillo, Silvio Danese, Raimondo De Cristofaro, Giovanni Scambia and Sergio Rutella

    Citation: Journal of Translational Medicine 2010 8:114

    Content type: Research

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  15. Peripheral immune tolerance requires a finely controlled balance between tolerance to self-antigens and protective immunity against enteric and invading pathogens. Self-reactive T cells sometimes escape thymic...

    Authors: Eva d'Hennezel, Mara Kornete and Ciriaco A Piccirillo

    Citation: Journal of Translational Medicine 2010 8:113

    Content type: Review

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  16. Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is associated with cancer progression and angiogenesis,...

    Authors: Rosaria Cammarota, Valentina Bertolini, Giuseppina Pennesi, Eraldo O Bucci, Ornella Gottardi, Cecilia Garlanda, Luigi Laghi, Massimo C Barberis, Fausto Sessa, Douglas M Noonan and Adriana Albini

    Citation: Journal of Translational Medicine 2010 8:112

    Content type: Research

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  17. The immune defects occurring in chronic lymphocytic leukemia are responsible for the frequent occurrence of infections and autoimmune phenomena, and may be involved in the initiation and maintenance of the mal...

    Authors: Marina Motta, Marco Chiarini, Claudia Ghidini, Cinzia Zanotti, Cinzia Lamorgese, Luigi Caimi, Giuseppe Rossi and Luisa Imberti

    Citation: Journal of Translational Medicine 2010 8:111

    Content type: Research

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  18. Epidemiological, preclinical and clinical studies demonstrated that chronic inflammation induced by hepatitis C virus (HCV) is crucial in hepatocellular carcinogenesis. The interaction between hepatocytes and ...

    Authors: Giuseppe Castello, Susan Costantini and Stefania Scala

    Citation: Journal of Translational Medicine 2010 8:109

    Content type: Review

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  19. Interferon is approved for adjuvant treatment of patients with stage IIb/III melanoma. The toxicity and uncertainty regarding survival benefits of interferon have qualified its acceptance, despite significant ...

    Authors: Helen Gogas, Urania Dafni, Henry Koon, Maria Spyropoulou-Vlachou, Yannis Metaxas, Elizabeth Buchbinder, Eirini Pectasides, Dimosthenis Tsoutsos, Aristidis Polyzos, Alexandros Stratigos, Christos Markopoulos, Petros Panagiotou, George Fountzilas, Ourania Castana, Pantelis Skarlos, Michael B Atkins…

    Citation: Journal of Translational Medicine 2010 8:108

    Content type: Research

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  20. The existence of circulating tumor cells (CTCs) in peripheral blood as an indicator of tumor recurrence has not been clearly established, particularly for gastric cancer patients. We conducted a retrospective ...

    Authors: Miao-zhen Qiu, Zhuang-hua Li, Zhi-wei Zhou, Yu-hong Li, Zhi-qiang Wang, Feng-hua Wang, Peng Huang, Fahad Aziz, Dao-yuan Wang and Rui-hua Xu

    Citation: Journal of Translational Medicine 2010 8:107

    Content type: Research

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  21. The complex data sets generated by higher-order polychromatic flow cytometry experiments are a challenge to analyze. Here we describe Exhaustive Expansion, a data analysis approach for deriving hundreds to tho...

    Authors: Janet C Siebert, Lian Wang, Daniel P Haley, Ann Romer, Bo Zheng, Wes Munsil, Kenton W Gregory and Edwin B Walker

    Citation: Journal of Translational Medicine 2010 8:106

    Content type: Methodology

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  22. The ability to expand virus- or tumor-specific T cells without damaging their functional capabilities is critical for success adoptive transfer immunotherapy of patients with opportunistic infection or tumor. ...

    Authors: Yixin Li and Roger J Kurlander

    Citation: Journal of Translational Medicine 2010 8:104

    Content type: Research

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  23. We previously reported that measuring circulating serum mRNAs using quantitative one-step real-time RT-PCR was clinically useful for detecting malignancies and determining prognosis. The aim of our study was t...

    Authors: Shunsaku Takahashi, Norimasa Miura, Tomomi Harada, ZhongZhi Wang, Xinhui Wang, Hideyuki Tsubokura, Yoshiaki Oshima, Junichi Hasegawa, Yoshimi Inagaki and Goshi Shiota

    Citation: Journal of Translational Medicine 2010 8:103

    Content type: Research

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  24. Cancer invasion results from constant interactions between cancer cells and their microenvironment. Major components of the cancer microenvironment are stromal cells, infiltrating inflammatory cells, collagens...

    Authors: Chun-Wei Peng, Xiu-Li Liu, Xiong Liu and Yan Li

    Citation: Journal of Translational Medicine 2010 8:101

    Content type: Research

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  25. Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor. A small contingent of clinical researchers are f...

    Authors: Michelle J Hickey, Colin C Malone, Kate L Erickson, Martin R Jadus, Robert M Prins, Linda M Liau and Carol A Kruse

    Citation: Journal of Translational Medicine 2010 8:100

    Content type: Review

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  26. Tumor immune responses are first generated and metastases often begin in tumor sentinel lymph nodes (TSLN). Therefore, it is important to promote tumor immunity within this microenvironment. Mifepristone (RU48...

    Authors: Claudia Raja Gabaglia, Alexandra DeLaney, Jennifer Gee, Ramesh Halder, Frank L Graham, Jack Gauldie, Eli E Sercarz and Todd A Braciak

    Citation: Journal of Translational Medicine 2010 8:98

    Content type: Research

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  27. Little is known about the induction of humoral responses directed against human autoantigens during acute inflammation. We utilized a highly sensitive antibody profiling technology to study autoantibodies in p...

    Authors: Peter D Burbelo, Nitin Seam, Sandra Groot, Kathryn H Ching, Brian L Han, G Umberto Meduri, Michael J Iadarola and Anthony F Suffredini

    Citation: Journal of Translational Medicine 2010 8:97

    Content type: Research

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