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Cardiovascular, metabolic and Lipoprotein translation

Section edited by Nehal N. Mehta

This section aims to speed mechanistic understanding, development of novel diagnostics and potential therapeutic targets within cardiovascular, metabolic diseases and lipoprotein diseases. The section is open to experiments involving cellular models, animal models, observational studies and clinical trials that are distinguished for their novelty in approach, design or indication, timeliness, and unique ability to translate laboratory concepts from the bench to the bedside.

Highest priority will be given to those manuscripts which are specifically focused on cardiovascular, metabolic and lipid disorders which enrich understanding of disease mechanism, novel therapeutics and state-of-the-art scientific technique.

Featured articles

Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease
Duy M. Ha, et al

Combining patient proteomics and in vitro cardiomyocyte phenotype testing to identify potential mediators of heart failure with preserved ejection fraction
Roseanne Raphael, et al

Chronic, not acute, skin-specific inflammation promotes thrombosis in psoriasis murine models.
Jackelyn B. Golden, et al

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  1. High burden of chronic cardio-metabolic disorders including type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), and cardiovascular disease (CVD) have been reported in the Middle East and North Afric...

    Authors: Samaneh Asgari, Fatemeh Moosaie, Davood Khalili, Fereidoun Azizi and Farzad Hadaegh

    Citation: Journal of Translational Medicine 2020 18:267

    Content type: Research

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  2. Aim of this study was to assess changes in cardiac morphometric parameters at different stages of pulmonary arterial hypertension (PAH) using a monocrotaline-induced rat model.

    Authors: Mateusz K. Hołda, Elżbieta Szczepanek, Joanna Bielawska, Natalia Palka, Dorota Wojtysiak, Paulina Frączek, Michał Nowakowski, Natalia Sowińska, Zbigniew Arent, Piotr Podolec and Grzegorz Kopeć

    Citation: Journal of Translational Medicine 2020 18:262

    Content type: Research

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  3. Inflammation-related atherosclerotic peripheral vascular disease is a major end organ complication of diabetes mellitus that results in devastating morbidity and mortality. Extracellular vesicles (EVs) are nan...

    Authors: Sharon F. Wu, Nicole Noren Hooten, David W. Freeman, Nicolle A. Mode, Alan B. Zonderman and Michele K. Evans

    Citation: Journal of Translational Medicine 2020 18:230

    Content type: Research

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  4. Extracorporeal circulation during major cardiac surgery triggers a systemic inflammatory response affecting the clinical course and outcome. Recently, extracellular vesicle (EV) research has shed light onto a ...

    Authors: Lukas Wisgrill, Christian Lamm, Lena Hell, Johannes Thaler, Angelika Berger, Rene Weiss, Viktoria Weber, Harald Rinoesl, Michael J. Hiesmayr, Andreas Spittler and Martin H. Bernardi

    Citation: Journal of Translational Medicine 2020 18:202

    Content type: Research

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  5. Glutamate, a key intermediate in myocardial metabolism, may enhance myocardial recovery after ischemia and possibly reduce the incidence and severity of postoperative heart failure in coronary artery bypass su...

    Authors: Huiqi Jiang, Jonas Holm, Mårten Vidlund, Farkas Vanky, Örjan Friberg, Yanqi Yang and Rolf Svedjeholm

    Citation: Journal of Translational Medicine 2020 18:193

    Content type: Research

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  6. To detect the development, function and therapeutic potential of epicardial adipose tissue (EAT); analyze a related gene expression dataset, including data from neonates, infants, and children with congenital ...

    Authors: Li Ma, Wanting Shi, Xun Ma, Minghui Zou, Weidan Chen, Wenlei Li, Rongjun Zou and Xinxin Chen

    Citation: Journal of Translational Medicine 2020 18:111

    Content type: Research

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  7. Venoarterial extracorporeal membrane oxygenation (VA ECMO) is widely used in the treatment of circulatory failure, but repeatedly, its negative effects on the left ventricle (LV) have been observed. The purpos...

    Authors: Pavel Hála, Mikuláš Mlček, Petr Ošťádal, Michaela Popková, David Janák, Tomáš Bouček, Stanislav Lacko, Jaroslav Kudlička, Petr Neužil and Otomar Kittnar

    Citation: Journal of Translational Medicine 2020 18:75

    Content type: Research

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  8. Inflammation within the perivascular adipose tissue (PVAT) in obesity plays an important role in cardiovascular disorders. C-reactive protein (CRP) level in obesity patients is significantly increased and asso...

    Authors: Jia-Yuan Chen, Xiao-Lin Zhu, Wen-Hao Liu, Yong Xie, Hai-Feng Zhang, XiaoQiao Wang, Ru Ying, Zhi-Teng Chen, Mao-Xiong Wu, Qiong Qiu, Jing-Feng Wang and Yang-Xin Chen

    Citation: Journal of Translational Medicine 2020 18:68

    Content type: Research

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  9. Bioresorbable scaffold (BRS) Absorb™ clinical use has been stopped due to higher rate of device thrombosis. Scaffold struts persist longer than 2 years in the vessel wall. Second generation devices are being d...

    Authors: Viktor Kočka, Petr Toušek, Martin Kozel, Andrea Buono, Martin Hajšl, Libor Lisa, Tomáš Buděšínský, Martin Malý and Petr Widimský

    Citation: Journal of Translational Medicine 2020 18:33

    Content type: Research

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  10. Cardiovascular disease (CVD) is the leading cause of death in the world. Given the role of immune cells in atherosclerosis development and progression, effective methods for characterizing immune cell populati...

    Authors: Yvonne Baumer, Cristhian A. Gutierrez-Huerta, Ankit Saxena, Pradeep K. Dagur, Steven D. Langerman, Kosuke Tamura, Joniqua N. Ceasar, Marcus R. Andrews, Valerie Mitchell, Billy S. Collins, Quan Yu, Heather L. Teague, Martin P. Playford, Christopher K. E. Bleck, Nehal N. Mehta, J. Philip McCoy…

    Citation: Journal of Translational Medicine 2020 18:29

    Content type: Research

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  11. Tetralogy of Fallot (ToF) and Atrial Septal Defects (ASD) are the most common types of congenital heart diseases and a major cause of childhood morbidity and mortality. Cardiopulmonary bypass (CPB) is used dur...

    Authors: Federica Raggi, Davide Cangelosi, Pamela Becherini, Fabiola Blengio, Martina Morini, Massimo Acquaviva, Maria Luisa Belli, Giuseppe Panizzon, Giuseppe Cervo, Luigi Varesio, Alessandra Eva and Maria Carla Bosco

    Citation: Journal of Translational Medicine 2020 18:21

    Content type: Research

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  12. The objectives of the study were to characterize and quantify cellular inflammation and structural remodeling of human atria and correlate findings with molecular markers of inflammation and patient surrogate ...

    Authors: Christie M. Aguiar, Kareem Gawdat, Stephanie Legere, Jean Marshall, Ansar Hassan, Petra C. Kienesberger, Thomas Pulinilkunnil, Mathieu Castonguay, Keith R. Brunt and Jean-Francois Legare

    Citation: Journal of Translational Medicine 2019 17:413

    Content type: Research

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  13. Atherosclerosis preferentially develops in regions of disturbed flow (DF). Emerging evidence indicates that yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ), which are...

    Authors: Dandan Liu, Hang Lv, Qi Liu, Yanli Sun, Shenglong Hou, Lu Zhang, Mengyue Yang, Baihe Han, Gang wang, Xuedong Wang, Wenjuan Du, Honggang Nie, Ruoxi Zhang, Xingtao Huang, Jingbo Hou and Bo Yu

    Citation: Journal of Translational Medicine 2019 17:378

    Content type: Research

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  14. Adipokines in serum derive mainly from subcutaneous and visceral adipose tissues. Epicardial adipose tissue (EAT), being a relatively small but unique fat depot, probably does not make an important contributio...

    Authors: Kacper Toczylowski, Tomasz Hirnle, Dorota Harasiuk, Piotr Zabielski, Anna Lewczuk, Iwona Dmitruk, Monika Ksiazek, Artur Sulik, Jan Gorski, Adrian Chabowski and Marcin Baranowski

    Citation: Journal of Translational Medicine 2019 17:310

    Content type: Research

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  15. HMG-CoA reductase inhibitors (statins) are cholesterol-lowering drugs widely used to treat hypercholesterolemia and prevent cardiovascular disease. Statins are generally well tolerated, but adverse reactions m...

    Authors: Estela Lorza-Gil, Marta García-Arevalo, Bianca Cristine Favero, Maria Cristina C. Gomes-Marcondes and Helena C. F. Oliveira

    Citation: Journal of Translational Medicine 2019 17:285

    Content type: Research

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  16. Spaceflight or microgravity conditions cause myocardial atrophy and dysfunction, contributing to post-flight orthostatic intolerance. However, the underlying mechanisms remain incompletely understood and preve...

    Authors: Liwen Liang, Wenyi Yuan, Lina Qu, Huili Li, Lulu Zhang, Guo-Chang Fan and Tianqing Peng

    Citation: Journal of Translational Medicine 2019 17:279

    Content type: Research

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  17. Neointimal hyperplasia and its related arterial stiffness are the crucial pathophysiological features in atherosclerosis and in-stent restenosis. Cluster of differentiation 147 (CD147), a member of the immunog...

    Authors: Kisoo Pahk, Hyojin Noh, Chanmin Joung, Mi Jang, Hwa Young Song, Kyung Won Kim, Kihoon Han, Jong-Ik Hwang, Sungeun Kim and Won-Ki Kim

    Citation: Journal of Translational Medicine 2019 17:274

    Content type: Research

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  18. Macrophage cholesterol efflux capacity has been identified as a predictor for cardiovascular disease. We assessed the relationship between adipocyte-derived extracellular vesicle microRNAs and macrophage chole...

    Authors: Matthew D. Barberio, Lora J. Kasselman, Martin P. Playford, Samuel B. Epstein, Heather A. Renna, Madeleine Goldberg, Joshua DeLeon, Iryna Voloshyna, Ashley Barlev, Michael Salama, Sarah C. Ferrante, Evan P. Nadler, Nehal Mehta, Allison B. Reiss and Robert J. Freishtat

    Citation: Journal of Translational Medicine 2019 17:232

    Content type: Research

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  19. Chemotherapy-induced left ventricular dysfunction represents a major clinical problem, which is often only recognised at an advanced stage, when supportive therapy is ineffective. Although an early heart failu...

    Authors: Mária Lódi, Dániel Priksz, Gábor Áron Fülöp, Beáta Bódi, Alexandra Gyöngyösi, Lilla Nagy, Árpád Kovács, Attila Béla Kertész, Judit Kocsis, István Édes, Zoltán Csanádi, István Czuriga, Zoltán Kisvárday, Béla Juhász, István Lekli, Péter Bai…

    Citation: Journal of Translational Medicine 2019 17:229

    Content type: Research

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  20. Type 1 diabetes mellitus (T1DM) patients display increased risk of cardiovascular disease (CVD) and are characterized by a diminished regulatory T (Treg) cell content or function. Previous studies have shown a...

    Authors: Sergio Martínez-Hervás, Verónica Sánchez-García, Andrea Herrero-Cervera, Ángela Vinué, José Tomás Real, Juan F. Ascaso, Deborah Jane Burks and Herminia González-Navarro

    Citation: Journal of Translational Medicine 2019 17:222

    Content type: Research

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  21. Ovarian cancer (OC) is one of the leading causes for cancer-related deaths among women. MicroRNAs (miRs) have been proved to be vital to the development and progression of OC. Hence, the study aims to evaluate...

    Authors: Jun Dai, Rujia Wei, Peihai Zhang and Beihua Kong

    Citation: Journal of Translational Medicine 2019 17:190

    Content type: Research

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  22. ST-segment elevation myocardial infarction (STEMI) displays circadian variability with the highest incidence in the morning hours. Data on whether the time-of-day at symptom onset affects infarct size or patie...

    Authors: Hendrik B. Sager, Oliver Husser, Sabine Steffens, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Gjin Ndrepepa and Thorsten Kessler

    Citation: Journal of Translational Medicine 2019 17:180

    Content type: Research

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  23. The sodium–glucose cotransporter-2 (SGLT2) inhibitor canagliflozin has been shown to reduce major cardiovascular events in type 2 diabetic patients, with a pronounced decrease in hospitalization for heart fail...

    Authors: Alex Ali Sayour, Sevil Korkmaz-Icöz, Sivakkanan Loganathan, Mihály Ruppert, Viktor Nabil Sayour, Attila Oláh, Kálmán Benke, Maik Brune, Rita Benkő, Eszter Mária Horváth, Matthias Karck, Béla Merkely, Tamás Radovits and Gábor Szabó

    Citation: Journal of Translational Medicine 2019 17:127

    Content type: Research

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  24. Chronic low-grade inflammation and oxidative stress play important roles in the development of obesity-induced cardiac hypertrophy. Here, we investigated the role of Fibronectin type III domain containing 5 (F...

    Authors: Zhi Geng, Wen-Yong Fan, Bing Zhou, Chao Ye, Ying Tong, Ye-Bo Zhou and Xiao-Qing Xiong

    Citation: Journal of Translational Medicine 2019 17:107

    Content type: Research

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  25. Oxidized low-density lipoproteins and scavenger receptors (SRs) play an important role in the formation and development of atherosclerotic plaques. However, little is known about their presence in epicardial a...

    Authors: Concepción Santiago-Fernández, Luis M. Pérez-Belmonte, Mercedes Millán-Gómez, Inmaculada Moreno-Santos, Fernando Carrasco-Chinchilla, Amalio Ruiz-Salas, Luis Morcillo-Hidalgo, José M. Melero, Lourdes Garrido-Sánchez and Manuel Jiménez-Navarro

    Citation: Journal of Translational Medicine 2019 17:95

    Content type: Research

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  26. Hyperoxia-induced bronchopulmonary dysplasia (BPD) models are essential for better understanding and impacting on long-term pulmonary, cardiovascular, and neurological sequelae of this chronic disease. Only fe...

    Authors: Francesco Greco, Susanne Wiegert, Philipp Baumann, Sven Wellmann, Giovanni Pellegrini and Vincenzo Cannizzaro

    Citation: Journal of Translational Medicine 2019 17:91

    Content type: Research

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  27. Coronary artery disease (CAD) is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). The purpose of the present study was to discriminate the Indian CAD patients with...

    Authors: Ramu Adela, Podduturu Naveen Chander Reddy, Tarini Shankar Ghosh, Suruchi Aggarwal, Amit Kumar Yadav, Bhabatosh Das and Sanjay K. Banerjee

    Citation: Journal of Translational Medicine 2019 17:17

    Content type: Research

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  29. Vascular grafts are widely used as a treatment in coronary artery bypass surgery, hemodialysis, peripheral arterial bypass and congenital heart disease. Various types of synthetic and natural materials were ex...

    Authors: Tao Wang, Nianguo Dong, Huimin Yan, Sze Yue Wong, Wen Zhao, Kang Xu, Dong Wang, Song Li and Xuefeng Qiu

    Citation: Journal of Translational Medicine 2019 17:24

    Content type: Research

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  30. Vascular shear stress promotes endothelial cell sprouting in vitro. The impact of hemodynamic forces on microRNA (miRNA) and gene expression within growing vascular networks in vivo, however, remain poorly inv...

    Authors: Dominic Henn, Masood Abu-Halima, Dominik Wermke, Florian Falkner, Benjamin Thomas, Christoph Köpple, Nicole Ludwig, Matthias Schulte, Marc A. Brockmann, Yoo-Jin Kim, Justin M. Sacks, Ulrich Kneser, Andreas Keller, Eckart Meese and Volker J. Schmidt

    Citation: Journal of Translational Medicine 2019 17:22

    Content type: Research

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  31. T cells are key regulators of immunity and one of the cells recruited in atherosclerosis and participated in various stages of the development of atherosclerosis. Characterizing T-cell receptor (TCR) repertoir...

    Authors: Zhixiong Zhong, Heming Wu, Qifeng Zhang, Wei Zhong and Pingsen Zhao

    Citation: Journal of Translational Medicine 2019 17:21

    Content type: Research

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  32. Endothelial-dependent atherosclerosis develops in a non-random pattern in regions of vessel bending and bifurcations, where blood flow exhibits disturbed flow (DF) patterns. In contrast, uniform flow (UF), nor...

    Authors: Ian C. Harding, Ronodeep Mitra, Solomon A. Mensah, Ira M. Herman and Eno E. Ebong

    Citation: Journal of Translational Medicine 2018 16:364

    Content type: Research

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  33. Aortic aneurysm (AA) is defined as an enlargement of the aorta greater than 1.5 times its normal size. Early diagnosis of AA is challenging and mortality of AA is high. Curative pharmacological treatments for ...

    Authors: Zhao Cheng, Yang-zhao Zhou, Yin Wu, Qi-ying Wu, Xiao-bo Liao, Xian-ming Fu and Xin-min Zhou

    Citation: Journal of Translational Medicine 2018 16:354

    Content type: Review

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  34. To date the TGF-β1 activation mediated by integrin ανβ5 during fibrosis is well-known. This process has been shown also in the heart, where cardiac fibroblasts (CF) differentiate into α-smooth muscle actin (α-...

    Authors: Gianluca Lorenzo Perrucci, Veronica Antonietta Barbagallo, Maria Corlianò, Delfina Tosi, Rosaria Santoro, Patrizia Nigro, Paolo Poggio, Gaetano Bulfamante, Federico Lombardi and Giulio Pompilio

    Citation: Journal of Translational Medicine 2018 16:352

    Content type: Research

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  35. Patients with monogenic familial hypercholesterolemia (FH) have high risk for coronary artery disease (CAD). A recent FH Expert Panel suggested that FH was underdiagnosed and undertreated which needs early dia...

    Authors: Ye-Xuan Cao, Na-Qiong Wu, Di Sun, Hui-Hui Liu, Jing-Lu Jin, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Qiu-Ting Dong, Geng Liu, Qian Dong and Jian-Jun Li

    Citation: Journal of Translational Medicine 2018 16:345

    Content type: Research

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  36. Metabolic syndrome (MetS) has an increased prevalence (approximately 20–25% of the adult population) all over the world. Immunological function is significantly associated with the development of MetS, and Met...

    Authors: Shihui Fu, Yao Yao, Faqin Lv, Fu Zhang, Yali Zhao and Fuxin Luan

    Citation: Journal of Translational Medicine 2018 16:315

    Content type: Research

    Published on:

  37. Sirtuin 3 (Sirt3) is a key regulator of energy metabolism and oxidative stress. To investigate the role of Sirt3 in contrast-induced acute kidney injury (CIAKI), we established the model both in vivo and in vi...

    Authors: Qinghai Zhang, Xun Liu, Na li, Jihong Zhang, Jianmin Yang and Peili Bu

    Citation: Journal of Translational Medicine 2018 16:313

    Content type: Research

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  38. To examine serum angiopoietin-2 (Angpt-2) in relation to malnutrition, inflammation, atherosclerosis and cardiac valvular calcification, so-called MIAC syndrome and its predictive role in outcomes of peritonea...

    Authors: Xiaoxiao Yang, He Zhang, Yuanyuan Shi, Zanzhe Yu, Hao Yan, Zhaohui Ni, Jiaqi Qian and Wei Fang

    Citation: Journal of Translational Medicine 2018 16:312

    Content type: Research

    Published on:

  39. Scavenger receptor class B type 1 (SR-B1) plays an essential role in high density lipoprotein (HDL) metabolism. SR-B1 deficient (SR-B1 KO) mice are prone to atherosclerosis and exhibit abnormally large, choles...

    Authors: Susana Contreras-Duarte, Nicolás Santander, Ruth Birner-Gruenberger, Christian Wadsack, Attilio Rigotti and Dolores Busso

    Citation: Journal of Translational Medicine 2018 16:309

    Content type: Commentary

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  40. Cardiac resynchronization therapy (CRT) reduces symptoms, morbidity and mortality in chronic heart failure patients with wide QRS complexes. However, approximately one third of CRT patients are non-responders....

    Authors: Clémentine Andre, Eric Piver, Romain Perault, Arnaud Bisson, Julien Pucheux, Emmanuelle Vermes, Bertrand Pierre, Laurent Fauchier, Dominique Babuty and Nicolas Clementy

    Citation: Journal of Translational Medicine 2018 16:299

    Content type: Research

    Published on:

  41. Doxorubicin (DOX)-based chemotherapy for Hodgkin lymphoma (HL) yields excellent disease-free survival, but poses a substantial risk of subsequent left ventricular (LV) dysfunction and heart failure, typically ...

    Authors: Matteo Sarocchi, Matteo Bauckneht, Eleonora Arboscello, Selene Capitanio, Cecilia Marini, Silvia Morbelli, Maurizio Miglino, Angela Giovanna Congiu, Giorgio Ghigliotti, Manrico Balbi, Claudio Brunelli, Gianmario Sambuceti, Pietro Ameri and Paolo Spallarossa

    Citation: Journal of Translational Medicine 2018 16:295

    Content type: Research

    Published on:

  42. Conotruncal heart defect (CTD) is a complex congenital heart disease with a complex and poorly understood etiology. The transcriptional corepressor RIPPLY3 plays a pivotal role in heart development as a negati...

    Authors: Nanchao Hong, Erge Zhang, Qingjie Wang, Xiaoqing Zhang, Fen Li, Qihua Fu, Rang Xu, Yu Yu, Sun Chen, Yuejuan Xu and Kun Sun

    Citation: Journal of Translational Medicine 2018 16:260

    Content type: Research

    Published on:

  43. Cardiomyopathies are the most common clinical and genetic heterogeneity cardiac diseases, and genetic contribution in particular plays a major role in patients with primary cardiomyopathies. The aim of this st...

    Authors: Chaoxia Lu, Wei Wu, Fang Liu, Kunqi Yang, Jiacheng Li, Yaping Liu, Rongrong Wang, Nuo Si, Peng Gao, Yongtai Liu, Shuyang Zhang and Xue Zhang

    Citation: Journal of Translational Medicine 2018 16:241

    Content type: Research

    Published on:

  44. Individuals with arterial hypertension often have an autonomic nervous system (ANS) imbalance with predominance of sympathetic ANS. This predominance can lead to injury of several organs affecting its function...

    Authors: Arthur F. Vale, Juliana A. Carneiro, Paulo C. V. Jardim, Thiago V. Jardim, James Steele, James P. Fisher and Paulo Gentil

    Citation: Journal of Translational Medicine 2018 16:240

    Content type: Research

    Published on:

  45. To explore the association between systolic and diastolic blood pressure (SBP and DBP respectively) and pulse pressure (PP) with cardiovascular disease (CVD) and mortality events among Iranian patients with pr...

    Authors: Ashkan Hashemi, Sormeh Nourbakhsh, Samaneh Asgari, Mohammadhassan Mirbolouk, Fereidoun Azizi and Farzad Hadaegh

    Citation: Journal of Translational Medicine 2018 16:230

    Content type: Research

    Published on:

  46. YKL-40 (CHI3L1) is a novel biomarker for inflammation, tissue remodeling, and fibrosis, as well as cardiovascular diseases. We investigated the association between YKL-40 expression in epicardial adipose tissue (...

    Authors: Qing Wang, Hua Shen, Jie Min, Yang Gao, Kai Liu, Wang Xi, Jie Yang, Liang Yin, Jibin Xu, Jian Xiao and Zhinong Wang

    Citation: Journal of Translational Medicine 2018 16:229

    Content type: Research

    Published on:

  47. The globally rising obesity epidemic is associated with a broad spectrum of diseases including atherosclerosis and non-alcoholic fatty liver (NAFL) disease. In the past, research focused on the vasculature or ...

    Authors: Erik Taylor, Nasi Huang, Jacob Bodde, Andrew Ellison, Ronald Killiany, Markus Michael Bachschmid and James Hamilton

    Citation: Journal of Translational Medicine 2018 16:215

    Content type: Research

    Published on:

  48. MicroRNAs (miRNAs) are non-coding RNAs that function as regulators of gene expression and thereby contribute to the complex disease phenotypes. Hypertrophic cardiomyopathy (HCM) and Dilated cardiomyopathy (DCM...

    Authors: Mengmeng Li, Xiao Chen, Liang Chen, Kai Chen, Jianye Zhou and Jiangping Song

    Citation: Journal of Translational Medicine 2018 16:161

    Content type: Research

    Published on:

  49. Scavenger receptor class B type I (SR-BI) plays a key role in high density lipoproteins (HDL) metabolism. SR-BI deficiency in mice results in enhanced susceptibility to atherosclerosis with abnormal large, cho...

    Authors: Jia Cao, Yanyong Xu, Feifei Li, Liang Shang, Daping Fan and Hong Yu

    Citation: Journal of Translational Medicine 2018 16:155

    Content type: Research

    Published on:

  50. Discoidin domain receptor 1 (DDR1) is a collagen-activated receptor tyrosine kinase extensively implicated in diseases such as cancer, atherosclerosis and fibrosis. Multiple preclinical studies, performed usin...

    Authors: Solange Moll, Yukari Yasui, Ahmed Abed, Takeshi Murata, Hideaki Shimada, Akira Maeda, Naoshi Fukushima, Masakazu Kanamori, Sabine Uhles, Laura Badi, Thomas Cagarelli, Ivan Formentini, Faye Drawnel, Guy Georges, Tobias Bergauer, Rodolfo Gasser…

    Citation: Journal of Translational Medicine 2018 16:148

    Content type: Research

    Published on:

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