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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Validation of circulating histone detection by mass spectrometry for early diagnosis, prognosis, and management of critically ill septic patients

Fig. 3

Concentration of circulating histones H2B and H3 in plasma of ICU-controls, sepsis, and septic shock patients. Circulating histones were measured using LC–MS/MS using spike-in isotopic labelled peptides for absolute quantification. Groups were compared by the Kruskal–Wallis test. *P < 0.01. The number of subjects analyzed were ICU Controls (n = 9); Sepsis (n = 11); septic shock (SS) (n = 69)

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