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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Mitochondrial impairment and downregulation of Drp1 phosphorylation underlie the antiproliferative and proapoptotic effects of alantolactone on oral squamous cell carcinoma cells

Fig. 7

Drp1 is an important target of ALT against OSCC cells. A, B Western blot band of Drp1 protein expression after different treatments. We used 15 µM ALT to treat CAL27 cells and SCC9 cells. C, D p-Drp1 level relative to Drp1 level. E, F Cell viability was measured after being treated with ALT for 24 h. We used 10 µM ALT to treat CAL27 cells and 4 µM to treat SCC9 cells. (**p < 0.01, ***p < 0.001, ****p < 0.0001 versus the EV group, #p < 0.05, ####p < 0.0001 versus the EV + ALT group)

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