Plasma cytokines | Cohort | Metadata | Correlation | P-value | Q-value |
---|---|---|---|---|---|
CSF2 | ME/CFS | Sex (0 = female, 1 = male) | − 0.474 | 0.001 | 0.032 |
Control | Sex (0 = female, 1 = male) | − 0.465 | 0.001 | 0.042 | |
ME/CFS | IBS (0 = without IBS, 1 = with IBS) | 0.437 | 0.002 | 0.052 | |
ME/CFS | BMI | 0.596 | 0.000 | 0.000 | |
Control | BMI | 0.448 | 0.001 | 0.023 | |
ME/CFS | Physical function (SF-36) | − 0.539 | < 0.001 | 0.002 | |
ME/CFS | Physical component summary (SF-36) | − 0.459 | 0.001 | 0.035 | |
ME/CFS | General Fatigue (MFI-20) | 0.436 | 0.002 | 0.047 | |
Leptin | ME/CFS | Sex (0 = female, 1 = male) | − 0.414 | 0.003 | 0.086 |
Control | Sex (0 = female, 1 = male) | − 0.427 | 0.002 | 0.061 | |
ME/CFS | IBS (0 = without IBS, 1 = with IBS) | 0.433 | 0.002 | 0.052 | |
ME/CFS | BMI | 0.577 | < 0.001 | < 0.001 | |
Control | BMI | 0.475 | 0.001 | 0.018 | |
ME/CFS | Physical function (SF-36) | − 0.558 | < 0.001 | 0.002 | |
ME/CFS | Physical component summary (SF-36) | − 0.445 | 0.001 | 0.035 | |
ME/CFS | General fatigue (MFI-20) | 0.439 | 0.002 | 0.047 | |
CCL2 | ME/CFS | Age | 0.440 | 0.002 | 0.060 |
CXCL10 | ME/CFS | Age | 0.394 | 0.005 | 0.099 |
CCL11 | ME/CFS | Age | 0.431 | 0.002 | 0.060 |
TNFα | ME/CFS | BMI | 0.543 | < 0.001 | 0.001 |
ME/CFS | Physical function (SF-36) | − 0.508 | < 0.001 | 0.004 | |
ME/CFS | Physical component summary (SF-36) | − 0.432 | 0.002 | 0.035 | |
IL1RA | ME/CFS | BMI | 0.468 | 0.001 | 0.010 |
ME/CFS | Physical function (SF-36) | − 0.480 | < 0.001 | 0.007 | |
IL13 | ME/CFS | Reduced activity (MFI-20) | 0.482 | < 0.001 | 0.025 |
Plasma proteomics | Cohort | Metadata | Correlation | P-value | Q-value |
---|---|---|---|---|---|
PROS1 | Control | Physical component summary (SF-36) | − 0.608 | < 0.001 | 0.008 |
Control | General fatigue (MFI-20) | 0.590 | < 0.001 | 0.016 | |
Control | Vitality (SF-36) | − 0.590 | < 0.001 | 0.015 | |
FCRL3 | Control | Vitality (SF-36) | − 0.538 | < 0.001 | 0.039 |
IGHV3-23.IGHV3-30 | Control | Vitality (SF-36) | 0.527 | < 0.001 | 0.039 |
SERPINA5 | ME/CFS | General health (SF-36) | 0.646 | < 0.001 | 0.004 |
ME/CFS | Social functioning (SF-36) | 0.593 | < 0.001 | 0.027 | |
CETP | Control | General fatigue (MFI-20) | 0.547 | < 0.001 | 0.032 |
Control | Total (MFI-20) | 0.557 | < 0.001 | 0.025 | |
HBA1 | Control | Mental fatigue (MFI-20) | − 0.558 | < 0.001 | 0.046 |
Control | Total (MFI-20) | − 0.556 | < 0.001 | 0.025 |