SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion

Table 1 Associations between SYTL2 expression and clinicopathological characteristics of PCa patients in the FFPE-SYSCC cohort

Clinical feature	Total patients n	Low n	High n	P value
Age
≤ 65	45	29	16	0.814
> 65	57	38	19	0.814
Gleason score
≤ 3 + 4	43	39	4	< 0.001^***
≥ 4 + 3	59	28	31	< 0.001^***
T state
T1–2	20	15	5	0.237
T3–4	50	30	20	0.237
Lymph node metastasis
N0	41	32	9	0.006^**
N1	30	14	16	0.006^**
Distant metastasis
M0	21	15	6	0.108
M1	25	12	13	0.108

A total of 102 paraffin-embedded PCa tissues were collected. Some samples lacked clinicopathological information, in which 32 samples lacked T stage information and 31 lacked lymph node metastasis information. Only 46 samples obtained distant metastasis information. Bold indicates p-value < 0.05 was considered significant. **p < 0.01, ***p < 0.001

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