Fig. 7

Gene expression and proteomics analysis of Panc-1 cells exposed to Okadaic Acid. A Cells were exposed to 20 nM of Okadaic Acid for 24 h (OA-SH) and OA resistant clones OA7A and OA7G were analyzed. For EMT gene expression we compared to the published data for OA24h (treated vs untreated: GSE114288). Gene expression of clones was relative to three independent untreated samples. B PP2A-gene expression. C EMT protein expression; control and OA-treated Panc-1 cells were analyzed in triplicate. Changes were determined relative to untreated Panc-1 cells as described in the materials and methods section. D PP2A proteins that were detected in the output list. Hierarchical clustering was used to present the levels. A color scale was used to visualize the expression: red is for increased and green indicates reduced expression versus the untreated control, grey: not present