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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality

Fig. 1

Gene set enrichment analysis of GSE15471 samples. A List of top hallmark gene sets enriched in tumor versus non-tumor samples. B Enrichment plot for Epithelial-Mesenchymal Transition. C Hierarchical clustering of the expression of EMT genes in the hallmark gene set. A color scale was used to visualize the expression: red is for increased and blue indicates reduced expression. D Enrichment plot for Hallmark genes upregulated in KRAS signaling. NES = normalized enrichment score. GSEA unsupervised analysis and Enrichments plots were obtained using GSEA software version 4.1.0 (release July 2021) and Molecular Signature Database (MSigDB) 7.4 hallmark gene sets [release April 2021, 13]

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