Fig. 3
From: Infantile hemangioma models: is the needle in a haystack?
Transviral model. The animal model of IH was established by microinjection of PyMT transgenic DNA. The constructed transgenic PyMT was injected into fertilized mouse embryos and then transferred into the uterus of pseudopregnant mice. After birth, it was found that the mouse IH model of transgenic PyMT DNA was successfully constructed, and IH was mainly distributed in the skin surface, tongue, ear mucosa and stomach mucosa. The PyMT gene was also expressed in transgenic mouse DNA.